Antifungal activity of fruit extracts of Flueggea leucopyrus Willd. Against phytopathogenic fungi Aspergillus spp.
Journal Title: IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) - Year 2019, Vol 14, Issue 1
Abstract
To study the phytoconstituents and antifungal activity of Flueggea leucopyrus fruit extracts of hexane, chloroform and methanol were tested against plant pathogenic fungi. The preliminary phytochemical analysis of the fruit extracts revealed the presence of oil in chloroform extract, oil and flavones in hexane extract, flavones, phenol and almost all the tested compounds in the methanol extract except coumarin and alkaloids. The TLC profile of the tested extracts showed two spots each (0.2, 0.4; 0.2, 0.5; 0.2, 0.6) for hexane, chloroform and methanol extracts respectively. Among the three extracts, the methanol extract showed significant activity by inhibiting the growth (Aspergillus fumigateus (23.3 mm), A. flavus (17.3 mm) and A. niger (16 mm). The secondary metabolic compounds like flavones, oil, phenol, quinones, saponins, sugar and tannins. The findings revealed that the phytoconstituents in the fruit extracts is highly resistant and can be used as a potential source for the development of new antifungal compounds. The preliminary phytochemical study was analyzed of the fruit extractions.
Authors and Affiliations
Ravi V, Thalavai Pandian A, Renuga R, Sivapriya O, P. Vijayakanth
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