Antifungal activity of Nigella sativa L. and Thymbra spicata L. essential oils against Tricophyton rubrum
Journal Title: Proceedings of the International Conference on Advanced Materials and Systems (ICAMS) - Year 2018, Vol 1, Issue
Abstract
In this study, we aimed to investigate components and the antifungal activity of Nigella sativa L. and Thymbra spicata L. essential oils against Tricophyton rubrum. Thirty-nine essential oil components, representing 99,69 %, were detected in the essential oil of Thymbra spicata L. The major essential oil constituents were carvacrol (58,32 %), γ-terpinene(28,53 %),o-cymene (5,20 %) and α-terpinene (2,03 %). Twenty-four essential oil components, representing 98,39 %, were detected in the essential oil of Nigella sativa L. The major essential oil constituents were anethole (22.97 %), thymoquinone (21.36 %), α-thujene (6.22 %), longifolene (5.76 %), trans-isoeugenol (3.55 %) and carvacrol (2.23 %). Antifungal activity of the essential oils of Nigella Sativa and Thymbra spicata was evaluated microdilution method. Fluconazole was selected as the standard antifungal drug. The activity of Nigella sativa L. and Thymbra spicata L. essential oils against T. rubrum was quite high. While Nigella sativa L. essential oils had MIC and MBC values of 1 and 2, Thymbra spicata L. essential oils were remarkable against T. rubrum. Thymbra spicata L. essential oils had the best MIC and MBC values (6.25 and 12.5 mg/ml). In our study, the efficacy of Thymbra spicata L. essential oils against Tricophyton rubrum was found higher. It seems that the essential oils of Nigella sativa L. and Thymbra spicata L. contain active components against rubrum, which is an important effect of superficial fungal infections.
Authors and Affiliations
Durmuș Alpaslan Kaya, Nizami Duran
Keywords
Related Articles
- EP ID EP603125
- DOI 10.24264/icams-2018.VIII.9
- Views 134
- Downloads 0
Influence of the formulation and preparation technique on the flufenamic acid release from different collagenic supports designed for wound healing
Drug delivery systems with controlled release are one of the top applications for human health, a new domain in material science with biomedical application. The aim of this study was to obtain and characterize some drug...
Manufacturing and properties of nonwovens based on waste from elastic fibers
The article proposes and implements the use of highly flexible combined filament yarns (Nylon 6.6/Lycra) as the main raw material for the production of needle-punched nonwoven materials for technical purposes. It has bee...
Functional finishing of textiles using bioactive agents based on natural products
There is nowadays an increasing vogue for so-called cosmetic textiles which are essentially garments that are designed to come into contact with the skin, which then transfer some active substances that may be used for c...
Tannin-inspired hydrogels with considerable self-healing and adhesive properties
Hydrogel materials are attracting considerable attention owing to their wide applications such as wound closure, drug delivery, tissue engineering, cell therapy, wrinkle fillers, etc. Considering the unique tannin chemis...
In-situ modified antimony-film glassy carbon electrode for metal trace analysis
Glassy carbon electrodes (GCE) have been extensively employed for the determination of trace amounts of heavy metals. Lately, modifications of GCE are currently being sought. One way of obtaining better analytical perfor...