Antifungal activity of Origanum syriacum L. essential oils against Candida spp.
Journal Title: Proceedings of the International Conference on Advanced Materials and Systems (ICAMS) - Year 2018, Vol 1, Issue
Abstract
The infections caused by Candida species have been reported to cause serious life-threatening infections. Because the increased drug resistance among candida spp., new drug researches are intensively carried out. Origanum syriacum L. is a valuable medicinal plant in terms of its components. The aim of this study was to investigate components and the antifungal activity of Origanum syriacum L. essential oils on the growth of Candida spp. By GC-MS was highlighted that thymol (42,18 %), carvacrol (33,95 %), cymene (8,87 %) and γ-terpinene (8,21 %) are the main components. Antifungal activity of the essential oils of Origanum syriacum L. was evaluated by microdilution method. The most notable activity was obtained against C. dubliniensis, C. albicans and C. parapsilosis. MIC values were found to be 15.6 C. for C. dubliniensis and 31.2 µg/ml for C. parapsilosis and C. albicans. MIC values against C. glabrata, C. kefyr, C. intermedia were found to be 62.5, MIC values for C. krusei and C. glabrata were 125 µg/ml. The highest activity in terms of MBC values in the study was obtained against C. intermedia and C. parapsilosis (62.5 µg/ml). Our results are particularly promising to have significant activity against C. dubliniensis, C. albicans and C. parapsilosis. Origanum syriacum L. essential oils, which were also effective against non-albicans Candida species, may be a new hope for the treatment of candida infections.
Authors and Affiliations
Nizami Duran, Durmuș Alpaslan Kaya
Keywords
Related Articles
- EP ID EP602467
- DOI 10.24264/icams-2018.I.11
- Views 181
- Downloads 0
Novel myco-composite material obtained with Fusarium oxysporum
Modern world environmental challenges dictate the need for obtaining of alternative materials in various industrial sectors. Filamentous fungi strains are complex microorganisms that are able to produce rich enzymes batt...
Antibacterial and UV protective effects of cotton fabrics dyed with Reseda luteola extract
Reseda luteola (Weld) extracts were used to dye textiles and decorate medieval manuscripts. The main components are luteolin and apigenin in the form of β-glucosides, having an important role in plant UV protection, colo...
Influence of the formulation and preparation technique on the flufenamic acid release from different collagenic supports designed for wound healing
Drug delivery systems with controlled release are one of the top applications for human health, a new domain in material science with biomedical application. The aim of this study was to obtain and characterize some drug...
Physical and chemical assessment of a patrimony sample
The objective of this paper was to investigate the physical and chemical properties of a sample from a national heritage private collection from the beginning of the 20th century. The fibrous composition was determined b...
Studies on structural, surface morphological, optical, luminescence and UV photodetection properties of sol gel oxides thin films
ZnO and ZnCoO thin films have been deposited onto glass substrates by sol–gel spin coating method. Zinc acetate dihydrate, cobalt acetate tetrahydrate, Isopropanol and monoethanolamine (MEA) were used as a precursor, dop...