Antifungal Drugs Loaded Nanosponges to Improve Bioavailability of Antifungal Drugs; A Review
Journal Title: Open Access Journal of Pharmaceutical Research - Year 2021, Vol 5, Issue 4
Abstract
Fungal infections have become a major concern in this era for human health leading to morbidity and mortality. A lot of antifungal agents are available for treatment, with poor therapeutic outcomes due to poor bioavailability, toxicity, and resistance challenges. Ordinary dosage forms are unable to meet the clinical needs. Nanosponges provide a promising drug delivery system overcoming major challenges concerned with antifungal agents. Nanosponges improves solubility, permeation, taste masking and stability of antifungal agents. It serves as an important tool for providing controlled release dosage forms. The nanosponges are easier to formulate and convenient for bilk manufacturing. Nanosponges thus provide various benefits to clinician to cope the overcoming demand of fungal infectious disease.
Authors and Affiliations
Qaiser M, Shahzad Q*, Hamza M and Hussain S
Keywords
Related Articles
- EP ID EP748597
- DOI 10.23880/oajpr-16000255
- Views 47
- Downloads 0
Medical Imaging Scans: A Short Letter
The medical imaging scans of various organs of the body have become an indispensable tool for medical fraternity which helps them in planning various surgical procedures. These scans depict the anatomical, structural and...
Antihyperlipidemic and Antibacterial Activities of Baccaurea Courtallensis Leaves
The present study evaluated the antihyperlipidemic and antibacterial activities of B. courtallensis extract. The antihyperlipidemic effect of B. courtallensis methanol extract was studied in Triton WR-1339 and high fat d...
Benomyl- or Carbendazim-Induced Androgen Receptor Disrupting Might Lead to Spinal and Bulbar Muscular Atrophy in Multi-Generations of Rats
We have reported that benomyl and its metabolite carbendazim induced reproductive and developmental toxicity and endocrine-disrupting activity in rats. The exactly underlying mechanism of reproductive and developmental t...
CDP-Choline Effect on Arthritis Model in Rat
CDP-choline is a naturally occurring endogenous nucleotide, which after administration rapidly metabolizes to choline (which is a natural α7nAChR selective Agonist) and cytidine/uridine. In the body, Choline promotes sev...
Trametes Versicolor and Dictyophora Indusiata Champions of Medicinal Mushrooms
Overall, studies both on the chemistry and pharmacology of Trametes versicolor and Dictyophora indusiata extracts and compounds are increasing in recent years and show therapeutic potential for various pathologies. The p...