Antifungal Screening of Curcuma longa and Zingiber officinale against Dermatophytes Causing Superficial Mycosis
Journal Title: International Journal of Pharma Research and Health Sciences - Year 2017, Vol 5, Issue 6
Abstract
The antifungal potential of Curcuma longa (turmeric) and Zingiber officinale (ginger) essential oils alone and in combinations, against common causes of dermatophytic infections in humans was investigated via in vitro investigations, in order to determine a suitable dosage for use in clinical trials. The antifungal activity of oils was screened against Trichophytonmentagrophytes and Microsporum audouiniiby using disc diffusion method.C. longa (turmeric) oil showed good antifungal activity (55 mmand 57mm), Z. officinale(ginger) oil had also good antifungal activity (69 mm and 59 mm) against T. mentagrophyte andM. Audouinii respectively as compared to reference antibiotics i.e. Clotrimazole (39mm against T.mentagrophyte & 45mm againstM. audouinii) Ketoconazole (34mm against T.mentagrophyte, 36 mm againstM. audouinii).The present study provides a scientific validation for the use of these essential oils in the treatment of superficial fungal infections.
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