Antilithiatic Potential Of Herbo-Mineral Formulations Sindhuvallathy Mezhugu(Svm) And Kalladaippu Kudineer (Kk) Against Ethylene Glycol Induced Nephrolithiasis.
Journal Title: IOSR Journal of Pharmacy (IOSRPHR) - Year 2018, Vol 8, Issue 4
Abstract
Kidney stones are hard masses formed at anywhere in the urinary system, leads to blood in the urine, urinary iritation and pain in the abdomen, flank, or groin by multiple causes like concentrated urine, excessive excretion of stone forming agents etc by improper food and lifestyle. Urolithiasis, nephrolithiasis, renal stones, kalladaippu are different terminologies used to mention this multifactorial disorder which has been tormenting mankind from the dawn of civilization. Present day conventional medications and measures for this disease remain unfriendly to mediocre population as they are highly expensive and not free from side effects. The Siddha system of medicine uniquely stands as an ancient heritage of south India and offers enormous herbal and herbo-mineral formulations for the prevention and management of kalladaippu. In this present study, the Siddha formulations Sindhuvallathy mezhugu (SVM), kalladaippu kudineer (KK) and a combination of both (SVM+KK) were evaluated for antilithiatic activity against Ethylene glycol (EG) induced hyperoxaluric Sprague Dawley rats. The study results supported that Sindhuvallathy mezhugu (SVM) and kalladaippu kudineer (KK) are safe and pharmacologically effective Siddha formulations and also they complement each other in the prevention and alleviation of nephrolithiasis.
Authors and Affiliations
Rajalakshmi K1, Jeeva Gladys R, Sukumar R, Logamanian M, Geetha lakshmi S5
Keywords
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