Antimicrobial activity of amoxicillin to the pathogens of respiratory diseases in pigs

Journal Title: Біологія тварин - Year 2014, Vol 16, Issue 2

Abstract

The effectiveness of antibiotic therapy in the treatment of respiratory diseases of bacterial etiology depends on the action spectrum of antimicrobial agent and the level of susceptibility of pathogen or pathogens of disease to his actions. The aim of the study was to investigate the antimicrobial activity of β-lactam antibiotic amoxicillin against microorganisms, pathogens of respiratory diseases in pigs. For studies from pigs 2 to 4 months of age with pneumonia biological material (blood, exudate from the nasal openings) was selected. Studies were conducted with recognized microbiological methods — by diffusion in agar using standard discs with antibiotics and the method of successive serial dilutions in liquid nutrient medium. Test of antimicrobial sensitivity of biomaterial microflora showed different levels of sensitivity of microorganisms to antibiotics, which primarily explains the unlike spectrum of activity of antibacterial agents. Based on the results of the test, microflora isolated from 80 % of samples proved to be sensitive to amoxicillin. Strains of Enterococcus faecalis, Streptococcus suis and Escherichia coli were isolated and identified from biological material. Accordingly of minimum inhibitory concentration (MIC) of amoxicillin 81.25 % of isolates of enterococci, and all isolates of streptococci and E. coli were susceptible and moderately susceptible. Results of determination of MICs of amoxicillin showed that this antibiotic exhibits a high level of bacteriostatic activity in relation to the selected strains and its action spectrum covers both Gram-positive and Gram-negative bacteria. Research of sensitivity of bacteria, pathogens of pneumonia in pigs, to amoxicillin showed that this chemotherapeutic agent is antibiotic of broad-spectrum antimicrobial activity and remains the drug of choice in the treatment of swine respiratory infections of bacterial etiology caused by susceptible strains of microorganisms to amoxicillin.

Authors and Affiliations

T. I. Stetsko

Keywords

Related Articles

The ways to reduce contamination of microscopic fungi in bee pollen

The article describes different ways of reducing the contamination of microscopic fungi in bee pollen, that had qualitative physicochemical indices regarding water content, flavonoids content, active acidity and the cont...

Amphiphiles as tools for studying hypertonic cryohemolysis of mammalian erythrocytes

The paper is devoted to the studying of effect caused by representatives of some amphiphilic compounds on hypertonic cryohemolysis of erythrocytes of various mammalian species. There was comparatively studied sensitivit...

Analysis of results of serology monitoring of circovirus infection in swine in Ukraine for the period 2013–2015

The article presents the results of serological monitoring research among domestic pigs in the regions of Ukraine regarding circovirus infection during 2013–2015 years. The aim was to assess the immune status of domesti...

Efficiency of the use a new vitamin and mineral addition in the feeding of dairy cows in the conditions zone of Precarpathian

Presented material reflects the results of researches on the use of new vitamin and mineral addition (VMA) in the feeding of dairy cows and its influence on the intensity processes of exchange in the organism and level o...

Effect of glucose and partial dehydration on resistance of mammalian erythrocytes to hypertonic shock

The paper is devoted to the studying the resistance of human, rabbit and rat erythrocytes to the effect of hypertonic shock when changing an initial status of cells modified with glucose and 0.4 mol/l NaCl. The hemolysis...

Download PDF file
  • EP ID EP367122
  • DOI -
  • Views 64
  • Downloads 0

How To Cite

T. I. Stetsko (2014). Antimicrobial activity of amoxicillin to the pathogens of respiratory diseases in pigs. Біологія тварин, 16(2), 112-118. https://europub.co.uk/articles/-A-367122