Biochemical changes in serum of chickens as a result of the action of deoxynivalenol
Journal Title: Біологія тварин - Year 2016, Vol 18, Issue 3
Abstract
The article presents the results of studies of the impact of deoxynivalenol (DON) on chickens of Adler silver cross, especially on a daily and weekly body weight gain and changes in biochemical parameters of blood serum. It was proved that deoxynivalenol at a dose 70 mg/kg of body weight adversely affected chickens. After a week chickens which were treated with the toxin began to lag behind in their growth and development and at the end of the experiment they had the worst indices of average daily and average weekly increments and overall weight compared to chicks of other two groups. However, feeding chickens that received deoxynivalenol with feed mixed with 2 % Mycosorb® gradually improved these indicators so that they became almost equal to indices of the control group, and the feeding Mycosorb® withfeed completely leveled a negative influence of toxin. During the biochemical studies we revealed that the overall activity of alkaline phosphatase serum in poultry of 2nd experimental group on the 7th day of the experiment was 14.3 % higher (728.7±15.0 U/L; P<0.001) compared to the 1st and had tends to increase in accordance with the control group. The same dependence was kept also by the bone isoenzyme of alkaline phosphatase activity which was 1.55 times (P<0.001) higher than in the control group. Contradicting results were received at the research content of macronutrients in the poultry blood. Thus, the total concentration of calcium in the 2nd experimental group (receiving toxin and Mycosorb®) was 1.97±0.17 mmol/l, while in the group of chickens receiving only one toxin (1st research) its content was 21.8 % higher (P<0.05) and it was 2.52±0.002 mmol/l. On the 3rd week of the experiment the total calcium content in the 2nd experimental group tended to increase (2.55±0.12 mmol/l) and it was almost equal to this index in poultry of control and 1st experimental groups.
Authors and Affiliations
D. M. Ostrovsky
Keywords
Related Articles
- EP ID EP260495
- DOI 10.15407/animbiol18.03.071
- Views 126
- Downloads 0
Investigation of the antibacterial action of modified heterocyclic compounds of substituted acridones against Staphylococcus aureus
The results of the study of antibacterial activity and determination of minimum inhibitory concentration substituted acridones class by microdilution method against a Staphylococcus aureus are described in the article. T...
Copper toxicokinetics in rats under prolonged administration of metal nanocomposites (Ag, Cu, Fe, Mn dioxide) with food
Experimental model of nanocomposite of metals (NcMe) contained nanoparticles of Argentum (31.5±0.9 nm), Copper (70.0±5.0 nm), Iron (100.0±10.0 nm) and manganese dioxide (50.0±3.0 nm) in aliquots ratio with the final conc...
Gynecological clinical examination of primiparous cows of different breeds
It was established that realization of gynecological clinical examination of firstborn-cows 4 times a year with monthly control of condition of inner organs secured opportunely exposure of disease as the reason of sympto...
Antioxidant system state in blood of pigs under the conditions of respiratory diseases and application of medicinal products Flovet 30 % and Floricol
It has been determined that respiratory diseases of agricultural animals characterize the tension in the system of antioxidant protection and activation of peroxidation processes, as a result in organs there is an accumu...
The content of certain heavy metals in tissues and products of honey-bees under the condition of their feeding with native soy flour adding chloride and aquanano chrome citrate
The influence of feeding with native soy flour, adding chloride and aquanano chrome citrate, on the content of chrome, zink, cuprum, ferrum, cadmium, and plumbum in the tissues of a head, thorax, abdomen and the whole bo...