ANTIMICROBIAL ACTIVITY OF DIFFERENT THIOSEMICARBAZONE COMPOUNDS AGAINST MICROBIAL PATHOGENS
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2012, Vol 3, Issue 5
Abstract
Thiosemicarbazone belongs to a large group of thiourea derivatives, whose biological activities are a function of parent aldehyde or ketone moiety. They have been evaluated over the last 50 year as antiviral, antibacterial, antifungal, antimalarial, anticancer, leprosy, rheumatism, trypanosomiasis and coccidiodis. Thiosemicarbazones were prepared by simple process in which N4-thiosemicarbazone moiety was replaced by aliphatic, arylic and cyclic amines. Present study reported the anti-microbial activity of different thiosemicarbazone compounds against certain bacterial and fungal pathogens viz. Bacillus cereus, Staphylococcus epidermis, Moraxella cattarhalis, Staph. Saprophyticus, Candida albicans and Aspergillus flavans.
Authors and Affiliations
Parul Negi , Subhangkar Nandy , Arun Mahato
Keywords
Related Articles
- EP ID EP108784
- DOI -
- Views 81
- Downloads 0
PHARMACOGNOSTICAL PROFILES ON CICHORIUM INTYBUS LINN., LEAVES
India has one the oldest, richest and most diverse cultural traditions associated with the use of medicinal plants. The remarkable fact is that is it still living tradition. The members of resistant of microbial pathogen...
DEVELOPMENT AND VALIDATION OF REVERSED-PHASE HPLC METHOD FOR ESTIMATION OF ONDANSETRON HYDROCHLORIDE IN BULK DRUG
A simple, accurate rapid and precise RP-HPLC method has been developed and validated for determination of Ondansetron hydrochloride in bulk drug. The RP-HPLC separation was achieved on hypersil C18 column (216 mm, 4.6 mm...
ELASTIC LIPOSOME: DRUG DELIVERY ACROSS HUMAN SKIN
Transdermal drug delivery is hardly an old technology, since 1800’s and the technology is no longer just adhesive patches. Due to recent advances in technology and the ability to apply the drug to the site of action with...
HYPOGLYCEMIC, CELL MEMBRANE STABILITY, THROMBOLYTIC, TOTAL PHENOLIC CONTENT AND FREE RADICAL SCAVENGING ACTIVITIES OF METHANOLIC EXTRACT OF ZIZIPHUS MAURITIANA FRUITS (RHAMNACEAE)
The purpose of the present study was to evaluate in vitro free radical scavenging activity and total phenolic content; hypoglycemic activity, cell membrane stabilizing activity and thrombolytic activity in mice model of...
MANAGEMENT OF HYPERLIPIDAEMIA (MEDO ROGA) IN AYURVEDA – A REVIEW
Hyperlipidemia, hyperlipoproteinemia, or hyperlipidaemia (Medo Roga) is the condition of abnormally elevated level of any or all lipids and/or lipoproteins in the blood. It is the most common form of dyslipidaemia (whic...