Antimicrobial Activity of Leaf Extract of Anogeissus Leiocarpus (African Birch) On Some Selected Clinical Isolates.
Journal Title: IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) - Year 2018, Vol 13, Issue 4
Abstract
The comparative study on the antimicrobial activity of ethanolic and aqueous extracts of Anogeissus leiocarpus (African birch) leaf against Staphylococcus aureus, Pseudomonas aeruginosa, Streptococcus mutans was evaluated in this research. The phytochemical analysis of both ethanolic and aqueous leaf extracts of Anogeissus leiocarphus (African birch) revealed the presence of saponine, tannins, steroide, cardiac glycoside, flavonoide and anthraquinone. There was antimicrobial activity for ethanolic extract against the test organisms with higher zones of inhibition on Pseudomonas aeruginosa ranging from 14mm-18mm than Staphylococcus aureus which ranged from 11mm-17mm, followed by Streptococcus mutans which ranged from 10mm-15mm. However, the aqueous extract revealed higher activities (zones of inhibition ranging from 10mm-23mm) against the test bacteria .The Minimum Inhibitory Concentration (MIC) for both ethanolic and aqueous against bacteria had a range of 200g/ml -400g/ml and 100mg/ml-200mg/ml respectively. The Minimum Bactericidal Concentration (MBC) showed potency against the organisms mostly at 400mg/ml except for P.aeruginosa . The MIC and MBC values observed for both ethanolic and aqueous extracts of Anorgeissus leiocarpus (African birch) revealed effectiveness against infections caused especially by S. aureus, and S.mutans at high concentration. The plant extract and phytochemicals that have potentials should be purified and developed into agents which can be used as a preventive or treatment therapies against the test organisms in a challenging economy.
Authors and Affiliations
Dayok O, Dawang . , D. N . , Da’am, C. E
Keywords
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- EP ID EP395661
- DOI 10.9790/3008-1304063640
- Views 58
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