ANTIMICROBIAL ACTIVITY OF NANOPARTICLES: AN ALTERNATE AGAINST DRUG-RESISTANT PATHOGENIC MICROBES
Journal Title: European Journal of Pharmaceutical and Medical Research - Year 2018, Vol 5, Issue 8
Abstract
Antimicrobial agents, considered as miracle drugs, can be obtained from natural sources such as plant or animal or can be produce synthetically. They are used against various pathogens however, the misuse of these drugs has resulted in the development of drug resistance in pathogenic microbes, which is one of the biggest challenges in healthcare field and is a substantial global threat. Another concern that arises from this, is the spreading of the resistant organism. The alternative of conventional antimicrobial drugs is being studied and research. In the present situation, nanoparticles are considered as new and effective therapeutic agent. The exceptional physiochemical characteristics of nanoparticles with the addition of growth inhibitory capabilities against microorganisms led the increase in nanoparticle studies and their effective antimicrobial applications. In the past, silver was used as therapeutic agent to treats chronic wounds and burns moreover, copper was used for water cleaning. It is much apparent that many of the metallic compounds have antimicrobial characteristic. Present days, the convergence of biology and nanotechnology has taken metal in the form of nanoparticles as an effective agent as many microorganisms. Nanoparticles have unique and well organized chemical and physical characteristics that can be altered according to the situation. In addition to that, potential antimicrobial efficiency because of their large surface area to volume ratio has given them an upper hand over chemical antimicrobial agents which is now having problem of drug resistance in microorganisms.
Authors and Affiliations
Ambash Riaz
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PREVALENCE OF TRICHOMONAS VAGINALIS AMONG PREGNANT WOMEN ATTENDING ANTENATAL CARE (ANC), MARYAM ABACHA WOMEN AND CHILDREN HOSPITAL, SOKOTO, NIGERIA
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Medicinal plants have been a major source of therapeutic agents for alleviation and cure diseases. The antimicrobial activity of the extracts of three species of genus Hydrocotyle was analyzed by using well diffusion met...
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EVALUATION OF THE EFFICACY OF PANAX GINSENG SUPPLEMENT ON NICOTINE AND CHRONIC STRESS INDUCED REPRODUCTIVE TOXICITY IN MALE ALBINO WISTAR RATS
The current study assessed the efficacy of panax ginseng supplement in nicotine and stress induced reproductive toxicity in 48 male albino Wistars rats (150-200g body weight). The rats were grouped into two sets, the fir...