Antimicrobial and Analgesic Activity of Solanum torvum
Journal Title: Haya: The Saudi Journal of Life Sciences - Year 2018, Vol 3, Issue 6
Abstract
Abstract:The present investigation was conducted to evaluate antimicrobial and analgesic activities of ethanol extract from Solanum torvum (Family: Solanaceae)aerial parts. The bioactive compounds such as glycoside, tannins, sterols, saponins, flavonoids, carbohydrates and proteins are detected in ethanol extract shown promising antibacterial activity against gram positive bacteria viz. B. subtilis and S. aureus. Analgesic activity was evaluated against both thermal and chemical induced stimuli, which were evidenced from acetic acid induced writhing, tail immersion and formalin induced paw licking test. The assessment of peripheral analgesic effect of the ethanol extracts exhibited a significant percentage inhibition in the writhings which were induced by acetic acid in mice. Similarly test drug significantly increased the latency period in the tail immersion test and the formalin study showed that both the aphasic and tonic pain was blocked by the extract. The overall analgesic effect of ethanol extract (200 and 400 mg/kg body weight, p.o.) was lower than the standard drugs aspirin. The presence of flavonoid compounds in ethanol extract of Solanum torvum aerial parts may be responsible for the analgesic effect Keywords:Solanum torvum, Aspirin, Phytochemicals, Antibacterial activity, Analgesic activity.
Authors and Affiliations
Suman Acharyya, Babli Khatun
Keywords
Related Articles
- EP ID EP397793
- DOI -
- Views 111
- Downloads 0
Hypoglycemic Activity of Curcuma longa LinnRoot Extracts on Alloxan Induced Diabetic Rats
Abstract: Plants form the main ingredients of medicine in traditional system of healing and have been the source of inspiration for several major pharmaceutical drugs. In spite of great advances of modern scientific medi...
HPLC Based Identification of Water Soluble Vitamins and Nutraceutical Value of Three Common Grasses of West Bengal
Abstract:The purpose of the present work was to evaluate the proximate composition, minerals content (Na, K, Ca, Fe, Mg, Cu, Zn, Mn), simultaneous quantification of water soluble vitamins (like ascorbic acid, thiamine, r...
Fatty Acid Composition of Oil Extracted from Murrel Fish (Channa striata) From Marathwada Region
Abstract:The Murrel fish (Channa striata) is a of freshwater fish species, native to South Asian region and it contains high nutritional values. The murrel fish is a good source of Omega fatty acids and proteins, omega f...
Phenolics Content in Legume and Their Health Benefit: A Review
Abstract:Legumes provide good source of protein, complex carbohydrate, dietary fibre, essential vitamins and minerals and are used as food and feed purposes. In most of the developing countries, animal protein is expensi...
Evaluation of in Vitro Antimicrobial Activity of Flower Extract of Tabernaemontana divaricata against Oral Pathogens
Abstract:Tabernaemontana divaricata is commonly used for the treatment of various illnesses. In the present study crude flower extracts were made using four different solvents such as water, methanol, ethanol and chlorof...