Antimicrobial Resistance Profile of Urinary Isolates from Patients with Indwelling Urinary Catheter Diagnosed of Benign Prostate Hyperplasia in Bida, Niger State, Nigeria

Journal Title: Journal of Pharmaceutical Research International - Year 2016, Vol 11, Issue 3

Abstract

Antimicrobial resistance is increasing daily and a cause of major challenges in many countries. Indiscriminate antibiotic prescription is associated to a higher prevalence of antibiotic resistant bacteria. The incidence of antimicrobial resistance among urinary pathogens is also increasing and its treatment has become more complicated due to increasing resistance. Aims: The present study investigated the pattern of uropathogens and their antimicrobial resistance pattern among the clinical isolates to commercially available antibiotics that are often prescribed in UTI treatment. Materials and Methods: The research was a retrospective study carried out on January 2009 through November 2013 and was exempted from ethical approval. Three hundred and thirty one (331) bacterial pathogens were selected for this study as isolated at the Medical Microbiology Laboratory, Federal Medical Centre, Bida, Niger State. Data was coded, computed and analyzed using SPSS version 16.0. Results: Out of (331) isolates, the most prevalent isolate is Escherichia coli 247(74.6%) followed by Staphylococcus aureus 34(10.3%), Pseudomonas aeruginosa 29(8.8%), Klebsiella species 10(3.0%), Proteus species 10(3.0%) and least uropathogen Staphylococcus albus 1(0.3%). Mean resistance of isolated uropathogen to Augmentin (94.0%), followed by Ampicillin (93.4%), Gentamycin (90.0%), while least resistance are Nitrofurantoin (36.3%) and Levofloxacin (56.2%). Conclusion: It is quite alarming to note that almost all of the isolates included in this study were found resistant to multiple drugs (four or more antibiotics).

Authors and Affiliations

O. A. Akobi, H. E. Inyinbor, E. C. Akobi, E. G. Emumwen, S. O. Ogedengbe, E. O. Uzoigwe, R. O. Abayomi, E. F. Emumwen, O. V. Nwala, Y. A. Abaukaka

Keywords

Related Articles

The Comparative Effect of Medicinal Herb Feverfew with that of a Synthetic Parthenolide to Assess the Expression of Inducible Cyclo-oxygenase and Anti-inflammatory Activity

Aims: This paper describes the expression of inducible cyclooxygenase and anti-inflammatory of medicinal herb feverfew with a synthetic parthenolide. Study Design: In vivo model to study the expression of inducible cyclo...

Enhanced Growth-inhibitory Effect of Microemulsified Curcumin Formulation in Human Prostate Cancer LNCaP Cells

Aim: To assess the effect of curcumin microemulsified with non-ionic surfactant surfynol 465 W or dispersed using edible oils on prostate LNCaP cancer cell viability and glutathione status. Methodology: LNCaP cells were...

Acute and Sub-chronic Oral Toxicity of Anthocleista vogelii (Cabbage Tree) Root Hydroethanolic Extract in Albino Rats

Aims: The toxicity profile of Anthocleista vogelii ethanolic root extract was investigated in Albino rats due to its use in Nigerian ethno-medicine for the management of diabetes mellitus. Study Design: The acute and sub...

The Knowledge and Attitude of Practicing Dentists towards the Antibiotic Prescription: A Regional Study

Aims: To assess dentist’s knowledge and practice in relation antibiotic prescription and to investigate if they follow the current international guidelines. Methodology: In this cross sectional study a structured and pre...

Plants in Respiratory Disorders I- Anti-asthmatics, A Review

Aim of This Review: Respiratory disorders pose a big threat to life and constitute a major public health problem worldwide. This review is an attempt to bring together some of the common medicinal plants traditionally us...

Download PDF file
  • EP ID EP342506
  • DOI 10.9734/BJPR/2016/25109
  • Views 72
  • Downloads 0

How To Cite

O. A. Akobi, H. E. Inyinbor, E. C. Akobi, E. G. Emumwen, S. O. Ogedengbe, E. O. Uzoigwe, R. O. Abayomi, E. F. Emumwen, O. V. Nwala, Y. A. Abaukaka (2016). Antimicrobial Resistance Profile of Urinary Isolates from Patients with Indwelling Urinary Catheter Diagnosed of Benign Prostate Hyperplasia in Bida, Niger State, Nigeria. Journal of Pharmaceutical Research International, 11(3), 1-8. https://europub.co.uk/articles/-A-342506