Antimicrobial Resistance Profile of Urinary Isolates from Patients with Indwelling Urinary Catheter Diagnosed of Benign Prostate Hyperplasia in Bida, Niger State, Nigeria
Journal Title: Journal of Pharmaceutical Research International - Year 2016, Vol 11, Issue 3
Abstract
Antimicrobial resistance is increasing daily and a cause of major challenges in many countries. Indiscriminate antibiotic prescription is associated to a higher prevalence of antibiotic resistant bacteria. The incidence of antimicrobial resistance among urinary pathogens is also increasing and its treatment has become more complicated due to increasing resistance. Aims: The present study investigated the pattern of uropathogens and their antimicrobial resistance pattern among the clinical isolates to commercially available antibiotics that are often prescribed in UTI treatment. Materials and Methods: The research was a retrospective study carried out on January 2009 through November 2013 and was exempted from ethical approval. Three hundred and thirty one (331) bacterial pathogens were selected for this study as isolated at the Medical Microbiology Laboratory, Federal Medical Centre, Bida, Niger State. Data was coded, computed and analyzed using SPSS version 16.0. Results: Out of (331) isolates, the most prevalent isolate is Escherichia coli 247(74.6%) followed by Staphylococcus aureus 34(10.3%), Pseudomonas aeruginosa 29(8.8%), Klebsiella species 10(3.0%), Proteus species 10(3.0%) and least uropathogen Staphylococcus albus 1(0.3%). Mean resistance of isolated uropathogen to Augmentin (94.0%), followed by Ampicillin (93.4%), Gentamycin (90.0%), while least resistance are Nitrofurantoin (36.3%) and Levofloxacin (56.2%). Conclusion: It is quite alarming to note that almost all of the isolates included in this study were found resistant to multiple drugs (four or more antibiotics).
Authors and Affiliations
O. A. Akobi, H. E. Inyinbor, E. C. Akobi, E. G. Emumwen, S. O. Ogedengbe, E. O. Uzoigwe, R. O. Abayomi, E. F. Emumwen, O. V. Nwala, Y. A. Abaukaka
Keywords
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- EP ID EP342506
- DOI 10.9734/BJPR/2016/25109
- Views 53
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