Antimutagenic activity of rosmarinus officinalis L. by Ames test
Journal Title: Scientific Journal of Microbiology - Year 2014, Vol 3, Issue 7
Abstract
Plants are an important source of substanceswhich are claimed to induce anti-inflammatory and antioxidant effects. Rosemary(Rosmarinus officinalis L.) is a medicinal plant that has many uses intraditional medicine. In this study, of R. officinalis leaves extracts werescreened for their antimutagenic activity against sodium azide by Ames test.The results showed that of R. officinalis leaves extracts can inhibit mutagenicagent of sodium azide. Rosemary leaves extracts with the inhibition of 42.92%sodium azide, showed high potential in decreasing mutagenic agent.Antimutagenic activity was increased significantly when there were livermicrosome extract (S9).
Authors and Affiliations
A. Tajehmiri| Medical Biology Research Center, Kermanshah University of Medical Sciences, Kermanshah, IRAN., M. Ghasemi| Department of Microbiology, College of Basic Science, Lahijan Branch, Islamic Azad University, Lahijan, IRAN., F. P. Sabet| Department of Microbiology, College of Basic Science, Lahijan Branch, Islamic Azad University, Lahijan, IRAN., M. M. Chakoosari| Department of Microbiology, College of Basic Science, Lahijan Branch, Islamic Azad University, Lahijan, IRAN., N. Abdolahzadegan*| Department of Microbiology, College of Basic Science, Lahijan Branch, Islamic Azad University, Lahijan, IRAN.
Keywords
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- EP ID EP1191
- DOI 10.14196/sjm.v3i7.1623
- Views 478
- Downloads 31
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