ANTIOXIDANT ACTIVITIES OF INCLUSION COMPLEXES OF 2-(BENZOTHIAZOLYL-2’) HYDRAZONO-3-PHENYL 5-ARYLIDENE- 4- THIAZOLIDINONE DERIVATIVES WITH Β-CYCLODEXTRIN
Journal Title: International Journal of Pharmaceutical Sciences and Drug Research - Year 2017, Vol 9, Issue 1
Abstract
The present study focused on the preparation and antioxidant studies of inclusion complexes of some compounds of 4-Thiazolidinone derivatives with β-cyclodextrin. The inclusion complex has been prepared in order to increase solubility and bio-accessibility of the parent compound. The experiment was conducted by taking 2-Hydrazinobenzothiazole as a starting material and a series of compounds and their inclusion is prepared from it. Taking into account on their physical, thermal and spectral characteristics (UV, IR and NMR), the formation of compounds and their inclusion complex are confirmed. From the antioxidant activities of compounds and inclusion complex, it has been found that inclusion complex has displayed more effectively than the original compounds.
Authors and Affiliations
Simanchal Dash, B. K. Garnaik
Keywords
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- EP ID EP617654
- DOI 10.25004/IJPSDR.2017.090103
- Views 82
- Downloads 0
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