ANTIOXIDANT ACTIVITY AND BIOACTIVE CONSTITUENTS IN THE FRUITING BODIES OF HERICUM ERINACEUS PERS, AN EDIBLE MUSHROOM
Journal Title: International Journal of Pharmacy and Pharmaceutical Sciences - Year 2016, Vol 8, Issue 3
Abstract
Objectives: Hericium is a genus of mushrooms in the Hericiaceae family. Hericium erinaceus has been used for the treatment of various diseases for over 2000 y in China. The study investigated the bioactive components and antioxidant properties of the hot water extract from the fruiting body of H. erinaceus.Methods: The hot water extract of H. erinaceus was estimated for antioxidant potency using different analysis, such as 1,1-diphenyl-2-picryl-hydrazyl (DPPH) radical scavenging assay, ferric reducing antioxidant power (FRAP) assay, cupric ions reducing antioxidant capacity (CUPRAC) assay, metal ion chelation, erythrocyte hemolysis inhibition assay and compared with the reference standards. Total phenolic, flavonoid contents, and total antioxidant capacity were also determined using spectrophotometric methods.Results: H. erinaceus showed concentration dependent activity in all the assays with following EC50 values. DPPH (EC50= 2.13 mg/ml), FRAP (EC50= 7.57 mg/ml), CUPRAC (EC50= 0.97 mg/ml), ferrous ion chelation (EC50= 2.31 mg/ml) and erythrocytes hemolysis inhibition (EC50= 4.88 mg/ml). The total phenolic and flavonoid content in H. erinaceus was found to be 8.77 mg GAE/g and 5.62 mg RE/g respectively.Conclusion: It was concluded that the hot water extract of the H. erinaceus exhibit potent free radical scavenging activity and can be used as natural antioxidants owing to their significant antioxidant activity.Keywords: Antioxidant, Scavenging activity, Free radicals, Reducing power, Hericium erinaceus pers, Total flavonoids, Total phenolics
Authors and Affiliations
Charumathy M. , Sudha G. , Packialakshmi B.
Keywords
Related Articles
- EP ID EP577785
- DOI -
- Views 51
- Downloads 0
THE EFFECT OF HANDING MERCURY DROP ELECTRODE ON DIFFERENTIAL PULSE POLAROGRAPHIC BEHAVIOR AND DETERMINATION OF ROSUVASTATIN IN PURE AND PHARMACEUTICAL TABLETS
Objective: Developing a simple, accurate and very sensitive differential pulse polarographic method (DPPM) for determination of rosuvastatin (RSV) in pure and tablets dosage forms using handing mercury drop electrode (HM...
ACUTE AND SUB-ACUTE ORAL TOXICITY ASSESSMENT OF THE POLYHERBAL FORMULATION IN ALBINO WISTER RATS
Objective: Polyherbal formulation (PHF) is prepared from five herbs; these herbs are well-known and widely used in the traditional system of medicine for the treatment of diabetes and various diseases. Individually, each...
QUALITATIVE SCREENING OF PHYTOCHEMICAL AND COMPARATIVE STUDY OF DIETARY ANTIOXIDATIVE PROPERTIES OF THREE COMMONLY USED LEAFY VEGETABLES OF WEST BENGAL
Objective: The study was carried out to evaluate the phytochemical constituents of three very commonly used leafy vegetables of West Bengal namely Bacopa monnieri (Brahmi sak), Lagenaria siceraria (Lau sak) and Spinacia...
CURCUMIN-ZN-ARTEMETHER COMBINATION THERAPY FOR PLASMODIUM BERGHEI INFECTED MICE
Objective: Studies have shown that a new combination therapy with artemisinin derivatives and curcumin is unique, with potential advantages over known Artemisinin Combination Therapy (ACT). The problems of poor solubilit...
SYNTHESIS AND BIOLOGICAL ACTIVITIES OF SOME INDOLE ANALOGUES CONTAINING TRIAZOLE-5-THIOL AND THIAZOLOTRIAZOLE SYSTEMS
Objective: The present study aims at the synthesis and evaluation of antimicrobial and antioxidant activities of indole analogues incorporated with triazole and thiazolotriazole moieties.Methods: The newly synthesized co...