Antioxidant Activity and Phytochemistry Study of Combretum obanense Stem (Bak. F) Hutch. and Dalz
Journal Title: European Journal of Medicinal Plants - Year 2015, Vol 10, Issue 3
Abstract
Objective: The objective of the present study was designed to test the antioxidant activity and phytochemical property of the methanol/ methylene chloride (1:1) extract of Combretum obanense. Place and Duration of Study: The International Centre for Ethnomedicine and Drug Development (InterCEDD), 110 Aku Road Nsukka, Enugu State, Nigeria, between January 2014 and July 2014. Methodology: We had assessed methanol/methylene chloride (1:1) stem extract of C. obanense, for antioxidant potentials with the help of DPPH (1, 1-diphenyl-2-picryl hydrazyl) free radical scavenging, reducing power assay and phytochemical analysis. Results: The extract was capable of neutralizing the DPPH free radicals via hydrogen donating activity by 78.09, 80.13, 80.54, 80.45, and 76.99% at concentrations of 25, 50, 100, 200, and 400 µg/ml respectively while reducing power extract ranging from 0.7490±0.0017 to 0.16470.0007. Conclusion: The finding supports the traditional use of this plant in Nigeria traditional medicine. We recommend further research on these plant stem for possible isolation and characterization of the various active chemical substances which has the toxic and medicinal values.
Authors and Affiliations
M. K. Tchimene, O. W. Obonga, C. E. C. Ugwoke, F. I. Nwafor, M. M. Iwu
Keywords
Related Articles
- EP ID EP350117
- DOI 10.9734/EJMP/2015/19970
- Views 83
- Downloads 0
Evaluation of Antimicrobial Activity of Mentha piperita, Tragia involucrata (L) and Urtica massaica Used as Medicinal Plants in Tanzania
Aims: To evaluate antimicrobial activity of Mentha piperita, Tragia involucrata (L) and Urtica massaica used as medicinal plants in Tanzania. Study Design: Experimental study was carried out by using 96 wells micro dilut...
In-vitro Anti-bacterial Effects of Jatropha curcas on Salmonella Typhi and Salmonella Typhimurium Isolated from Presumptive Typhoid Fever Patients in Akure Metropolis, Nigeria
Aim: The present study determined the in-vitro anti-bacterial effects of Jatropha curcas on Salmonella Typhi and Salmonella Typhimurium isolated from presumptive typhoid fever patients in Akure metropolis, Nigeria. Stud...
Composition and Antimicrobial Activity of Leaf Essential Oils of Myrcia sylvatica (G. Mey.) DC.
Aims: The leaves of Myrcia sylvatica have traditional use in the control of dysentery and intestinal parasites for the riparian inhabitants who live in savanna areas along the Amazon River, Brazil. Methodology: The con...
Effects of Crude Extract of Dry Fruits of Piper guineense on Male Fertility Parameters of Adult Sprague Dawley Rats
Objective: To study the effect of aqueous extract of dry fruits of Piper guineense on male fertility parameters of adult male Sprague Dawley rats. Materials and Methods: 30 adult male Sprague Dawley rats weighing betwee...
In-vitro Evaluation of Antioxidant Potency of Organic Extracts of Leaves of Corchorus depressus Linn.
Aim: Evaluation of free radical scavenging and lipid peroxidation inhibitory activities of commercially available leaves of Corchorus depressus Linn. by in-vitro chemical analysis. Methodology: Four different solvent ext...