ANTIOXIDANT ACTIVITY OF LEAF EXTRACTS OF HEMIDESMUS INDICUS (L.) R.BR. (ASCLEPIADACEAE).
Journal Title: Asian Journal of Pharamceutical and Clinical Research - Year 2017, Vol 10, Issue 6
Abstract
Objective: A number of Indian medicinal plants have been used for thousands of years in a traditional system of medicine. Hemidesmus indicus is an important member of the Asclepiadaceae family. It is an endemic to the southern Western Ghats, India. The aim of the study was to investigate the free radical scavenging activity of H. indicus. Methods: The aqueous and methanol leaf extracts of H. indicus were assayed for radical scavenging activity, using the stable free radical 2,2-diphenyl- 1-picryl-hydrazyl-hydrate and 2,2’-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid). Results: The results revealed that the IC50 values of aqueous extract of H. indicus were found to be higher than that of the other solvent extracts. The free radical scavenging activity of the plant extracts may be due to the presence of phytoconstituents. Conclusion: In all the methods, the aqueous extract has exhibited the good scavenging activity and this arises that the plant has a potential antioxidant agent.
Authors and Affiliations
Abdul Kaffoor H, Muthuraj K, Arumugasamy K
ANTIBACTERIAL ACTIVITY, FREE RADICAL SCAVENGING POTENTIAL, PHYTOCHEMICAL INVESTIGATION AND IN-VIVO TOXICITY STUDIES OF MEDICINAL PLANT Embelia basaal (R. & S.) A. DC.
 Objective: Present extensive study on medicinal plant Embelia basaal (R. & S.) A. DC. was undertaken for evaluation and quantification of broadspectrum antibacterial activity, free radical scavenging potential, phy...
METFORMIN and SULFONYLUREAS EFFECT on the BLOOD LEVEL of PROSTATE SPECIFIC ANTIGEN
Objective: The aim of this study was to investigate the effect of metformin and sulfonylurea on the blood level of prostate specific antigen (PSA).Methods: 26 Type 2 diabetic patients under metformin treatment and 42 pat...
EVALUATION OF ANTI-INFLAMMATORY AND ANTI-ARTHRITIC POTENTIAL OF FRACTIONS OF ECLIPTA PROSTRATA LINN
Objective: The objective of the study was to establish the anti-inflammatory and anti-arthritic potential of various fractions of Eclipta prostrata Linn. Methods: The four fractions, i.e., n-butanol, ethyl acetate, chlo...
A PROSPECTIVE STUDY ON GERIATRIC PRESCRIBING PATTERN AND MEDICATION ADHERENCE IN A TERTIARY CARE HOSPITAL
  Objectives: To identify potentially inappropriate medications (PIMs) using Beers criteria 2015 and to recommend safer alternative medication for the above. To assess the medication adherence in geriatric patients and...
The protective effect of Zinc and Magnesium against subchronic Cadmium toxicity in Wistar rats (Biochemical and neurobehavioral effects)
Objective: The present study shows the beneficial effect of (zinc 10mg / kg + magnesium 10mg / kg) against cadmium poisoning at a dose of 15mg / kg on biochemical parameters and neurobehavioral functions in Wistar rats d...