Antioxidant activity of polysaccharide from Sargassum sp
Journal Title: IOSR Journal of Pharmacy (IOSRPHR) - Year 2018, Vol 8, Issue 8
Abstract
Brown seaweeds are widely used in the medical field to treat tumor cells. In this present study brown seaweed Sargassum species was used to isolate polysaccharide and quantitative estimation of carbohydrate was done and the free radical scavenging activity of the isolated polysaccharide was determined using DPPH radical scavenging assay, Hydrogen peroxide scavenging activity Nitric oxide scavenging activity , Ferric reducing antioxidant Power (FRAP) Deoxyribose Radical Scavenging Activity, ABTS [2, 2’-azinobis-(3- ethylbenzothiazoline-6-sulfonic acid)] Radical cation Scavenging Assay, Superoxide radical scavenging activity, Estimation of lipid peroxidation using egg yolks, β carotene linoleic acid assay and SOD was performed. The obtained results gave a significant IC50 Value which indicates that the isolated polysaccharide from the Sargassum sp was able to inhibit the free radicals and can be used to treat tumour cells.
Authors and Affiliations
Revathi Chitra S, Syed Ali M, Anuradha V, Shantha M, Yogananth .
Keywords
Related Articles
- EP ID EP382520
- DOI -
- Views 97
- Downloads 0
A Review on Current Trends of Nanotechnology for Cancer Therapy
Targeted drug delivery is an advanced method of delivering drugs to the patients in such a targeted sequences that increases the concentration of delivered drug to the targeted body part of interest only (organs/tissues/...
OSA: An awaking disorder!
OSA is characterized by repeated narrowing or collapse of the upper airway during sleep. It is the most common sleep disordered breathing seen among general population and contributes to increased morbidity and mor...
A high frequency microcloning protocol for subsequent cryopreservation in Kaempferia galanga L.: An endangered, over exploited medicinal plant in pharmaceutics
: An efficient in vitro propagation protocol was standardized in K. galanga, wherein shoot cultures were raised from rhizome with axillary bud explants in Murashige and Skoog (MS) medium supplemented with differe...
Therapeutic importance of Hyoscyamus species grown in Iraq (Hyoscyamus albus, Hyoscyamus niger and Hyoscyamus reticulates)- A review
Hyoscyamus is one of the most important and largest genera of the family Solanaceae comprising about 84 genera and more than 3000 species. All Hyoscyamus species are rich sources of tropane alkaloids, mainly hyoscyamine...