Antioxidant activity of polysaccharide from Sargassum sp
Journal Title: IOSR Journal of Pharmacy (IOSRPHR) - Year 2018, Vol 8, Issue 8
Abstract
Brown seaweeds are widely used in the medical field to treat tumor cells. In this present study brown seaweed Sargassum species was used to isolate polysaccharide and quantitative estimation of carbohydrate was done and the free radical scavenging activity of the isolated polysaccharide was determined using DPPH radical scavenging assay, Hydrogen peroxide scavenging activity Nitric oxide scavenging activity , Ferric reducing antioxidant Power (FRAP) Deoxyribose Radical Scavenging Activity, ABTS [2, 2’-azinobis-(3- ethylbenzothiazoline-6-sulfonic acid)] Radical cation Scavenging Assay, Superoxide radical scavenging activity, Estimation of lipid peroxidation using egg yolks, β carotene linoleic acid assay and SOD was performed. The obtained results gave a significant IC50 Value which indicates that the isolated polysaccharide from the Sargassum sp was able to inhibit the free radicals and can be used to treat tumour cells.
Authors and Affiliations
Revathi Chitra S, Syed Ali M, Anuradha V, Shantha M, Yogananth .
Keywords
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