Antioxidant and Anti-Inflammatory Activity of Proteins Isolated From ZingiberOfficinaleRoot
Journal Title: Scholars Academic Journal of Pharmacy - Year 2017, Vol 6, Issue 12
Abstract
To investigate the in vitro, antioxidant and anti-inflammatory activity of the proteins isolated fromZingiberofficinale, proteins isolated by Ammonium sulphate precipitation method. In vitro antioxidant studies were carried out for the proteins using superoxide radical scavenging method and anti-inflammatory studies was done using membrane stabilization assay. The superoxide radical scavenging ability of the proteins was compared with standard antioxidant like Alpha tocopherol and Ascorbic acid at a maximum dosage of 8µg, where Zingiberofficinaleroot protein showed a maximum inhibition of 55% and Alpha tocopherol and Ascorbic showed 55 and 51% respectively. The anti-inflammatory activity of Zingiberofficinaleroot proteins were compared with the standard drug Diclofenac sodium, where at a dosage of 1000µg/ml, plant root protein showed maximum inhibition where as the drug Diclofenac Sodium showed at a dosage of 200µg/ml. The results of the present study concluded that the Zingiberofficinaleroot proteins possess significant antioxidant and anti-inflammatory activity and it may due to the presence of proteins. Keywords:Zingiberofficinale, Ginger, proteins Antioxidant, Antiinflammant.
Authors and Affiliations
Chikkanna D, Santosh Kumar N, Subhas Chandrappa M, Dinesha R
Keywords
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