Choice of Drug Eluting Stent: A Review
Journal Title: Scholars Academic Journal of Pharmacy - Year 2014, Vol 3, Issue 2
Abstract
The development of stent has been a major achievement in treating obstructive coronary artery disease (OCAD). The main obstacle in the long term success of percutaneous coronary intervention (PCI) was the neo-intimal hyperplasia developed within the stent, which may leads to instent restenosis. The introduction of Drug-eluting stents (DES) shows steep decrease in angiographic restenosis when compared with bare metal stent. The ability of DES to prevent the restenosis after balloon angioplasty reduces the complications associated with sub acute stent thrombosis and late stent restenosis by decreasing the incidence of MI. The coating of bioabsorbable polymers on DES enhances antiproliferative drug release. This review article reveals various types of drug eluting stents and their comparison with bare metal stents. Keywords: Bare-metal stents, Drug-eluting stents, Brachytherapy
Authors and Affiliations
Jasmine George, Hari R, Lincy George, L. Panayappan ,, K Danova
Keywords
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