Antioxidant enzymosomes – properties and application
Journal Title: Advances in Hygiene and Experimental Medicine - Year 2011, Vol 65, Issue 0
Abstract
The application of catalase and superoxide dismutase in daily practice encounters many difficulties connected first of all with their loss of activity, and even with their degradation. Both enzymes, catalase and superoxide dismutase, practically do not penetrate biological membranes, which limits or even makes impossible their protective activity directed against ROS. However, the penetration of the membranous barrier becomes possible after the location of the enzymes in lipidic structures. One of the technologies of stabilization of the activity of enzymes consists in closing them in a liposome structure. The incorporation of the enzymes into a closed, such as liposome, structure or into their lipid bilayer screens and simultaneously protects them against degradation which they would undergo during use in the unshaded form. Concurrently it extends their half life and also increases their activity and stability. The structure in which an enzyme is enclosed in a liposome is called an enzymosome.
Authors and Affiliations
Magdalena Skólmowska, Marek Kmieć
Keywords
Related Articles
- EP ID EP66548
- DOI -
- Views 177
- Downloads 0
The role of the ERM protein family in maintaining cellular polarity, adhesion and regulation of cell motility
Ezrin, radixin and moesin, forming the ERM protein family, act as molecular crosslinkers between actin filaments and proteins anchored in the cell membrane. By participating in a complex intracellular network of signal...
Resistance of Pseudomonas aeruginosa to antibiotics
The main problem in the treatment of nosocomial infections is the increasing drug resistance of microorganisms that cause them, limiting the number of effective antibiotics. Pseudomonas aeruginosa bacilli are the cause o...
Substancje pochodzenia roślinnego przeciwdziałające kardiotoksyczności towarzyszącej chemioterapii nowotworów
Prawie wszystkie leki przeciwnowotworowe stosowane klinicznie wykazują właściwości toksyczne w stosunku do mięśnia sercowego. Kardiotoksyczność występująca podczas chemioterapii przeciwnowotworowej może być czynnikiem li...
Hypertension in the course of primary aldosteronism during pregnancy
Hypertension is one of the most common cardiovascular diseases during pregnancy. Primary hyperaldosteronism (PHA) is the most frequent endocrinological, secondary cause of hypertension, rarely diagnosed in pregnant women...
Zmiana elektropotencjałów w jamie ustnej po zastosowaniu impulsowego pola magnetycznego z zakresu ELF
Pojawiające się w jamie ustnej elektropotencjały nie są obojętne, gdyż mogą wywoływać różne schorzenia oraz powodować występowanie subiektywnych nieprzyjemnych odczuć, których leczenie jest bardzo trudne. Celem badań był...