Antipyretic activity of methanolic leaf extract of Canarium strictum Roxb.
Journal Title: Journal of Ayurvedic and Herbal Medicine - Year 2017, Vol 3, Issue 2
Abstract
The present study is aimed to investigate the antipyretic activity of methanolic leaf extract of Canarium strictum in wistar albino mice. Pyrexia was induced in mice by Brewer’s yeast suspension. The animals were divided in to 5 groups, 6 of each as following Group I received normal saline water (control); Group II received standard paracetamol 150 mg/kg; Group III, IV & V received methanolic leaf extract of C. strictum at doses 100, 200 & 300 mg/kg respectively. In all experiments, rats were orally administered. The temperature of all the mice in each group was measured at the start of study, at 18 h after yeast injection and every hourly for 4 h thereafter. The mean temperature was found out for each group and was compared with the control group and standard drug group. The C. strictum leaf extract at doses 200 and 300 mg/kg significantly reduced the body temperature on yeast induced pyrexia and was comparable with standard.
Authors and Affiliations
Venkatachalapathi A, H. Abdul Kaffoor, S. Paulsamy
Keywords
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