Apitoxin and its Anti-inflammatory activity and anti-nociceptive
Journal Title: ACTA Apicola Brasilica - Year 2014, Vol 2, Issue 2
Abstract
The bee venom is the poison used by bees of the genus Apis for their protection and defense against numerous natural enemies. Its composition is complex and consists of a mixture of enzymes (Fosfalipase A2 and Hialorunidase) peptides (Melittin, Apamin, and Peptide MCD), amines (histamine, dopamine, and noradrenaline) carbohydrates and lipids once inoculated apitoxin to trigger a series of biological reactions on the membrane, which vary according to the biochemical diversity of its constituents. In the present scenario, the bee venom production is a different activity within the beekeeping, with great potential for the pharmaceutical market, the ability to produce numerous drugs. In this paper, we focus on the production and collection of bee venom by addressing its chemical composition, its pharmacological properties and therapeutic activities, focused on its anti-inflammatory action and anti-nociceptive.
Authors and Affiliations
Edivaldo Ferreira Pacheco Filho, Fernando Magno Bitú Magalhães, Antônio Vitor Machado, Rubenia de Oliveira Costa
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