Application of Sigma Metrics and Performance Comparison Between Two Biochemistry Analyser and A Blood Gas Analyser for the Determination of Electrolytes

Journal Title: Journal of Clinical and Diagnostic Research - Year 2017, Vol 11, Issue 2

Abstract

Introduction: Electrolytes have a narrow range of biological variation and small changes are clinically significant. It is important to select the best method for clinical decision making and patient monitoring in the emergency room. The sigma metrics model provides an objective method to evaluate the performance of a method. Aim: To calculate sigma metrics for electrolytes measured with one arterial blood gas analyser including two auto-analysers that use different technologies. To identify the best approach for electrolyte monitoring in an emergency setting and the context of routine emergency room workflow. Materials and Methods: The Coefficient of Variation (CV) was determined from Internal Quality Control (IQC). Data was measured from July 2015 to January 2016 for all three analysers. The records of KBUD external quality data (Association of Clinical Biochemists, Istanbul, Turkey) for both Mindray BS-2000M analyser (Mindray, Shenzhen, China) and Architect C16000 (Abbott Diagnostics, Abbott Park, IL) and MLE clinical laboratory evaluation program (Washington, DC, USA) for Radiometer ABL 700 (Radiometer Trading, Copenhagen, Denmark) during the study period were used to determine the bias. Results: The calculated average sigma values for sodium (-1.1), potassium (3.3), and chloride (0.06) were with the Radiometer ABL700. All calculated sigma values were better than the autoanalysers. Conclusion: The sigma values obtained from all analysers suggest that running more controls and increasing the calibration frequency for electrolytes is necessary for quality assurance.

Authors and Affiliations

Yasemin Ustundag- Budak, Kagan Huysal

Keywords

Related Articles

Auxanographic Carbohydrate Assimilation Method for Large Scale Yeast Identification

Introduction: The auxanographic carbohydrate assimilation had been an important method for differentiation of yeasts. Prevailing methods described in the literature for carbohydrate assimilation has limited scope for use...

Blood Lead Levels in Children of Southwest Iran, Aged 2-6 Years and Associated Factors

Introduction: Lead is one of the toxic metals that can cause several complications in children. Aim: This study was conducted to determine Blood Lead Levels (BLLs) in healthy children and its association with individual...

Flexor Digitorum Profundus Irritation and Pseudotumour Formation Ten Years after a Penetrating Glass Injury

ABSTRACT Retained foreign bodies inside the soft tissue following penetrating injuries are common. Late onset of symptoms and complications are possible in these cases. In the present report, we present a case of late fl...

Olmesartan in Management of Proteinuria

ABSTRACT Proteinuria is a marker and predictor of cardiovascular morbidity and mortality. Blockade of angiotensin receptor might result in reduction in proteinuria. Olmesartan, an Angiotensin Receptor Blocker (ARB) whic...

Download PDF file
  • EP ID EP331844
  • DOI 10.7860/JCDR/2017/23486.92
  • Views 149
  • Downloads 0

How To Cite

Yasemin Ustundag- Budak, Kagan Huysal (2017). Application of Sigma Metrics and Performance Comparison Between Two Biochemistry Analyser and A Blood Gas Analyser for the Determination of Electrolytes. Journal of Clinical and Diagnostic Research, 11(2), 6-9. https://europub.co.uk/articles/-A-331844