APPRAISAL OF ANTIBIOTIC PROPHYLAXIS ADMINISTRATION IN GENERAL SURGERY DEPARTMENT OF A MAJOR REFERRAL HOSPITAL
Journal Title: Int J of Pharm Rev& Res - Year 2015, Vol 5, Issue 4
Abstract
Antibiotic prophylaxis use lead to substantial decrease in both quantity as well as variations of surgical site infections, although antibiotic prophylaxis practices are tend to be evidence based but generally either that evidence doesn’t have that much quality or recommended as expert opinion. To evaluate the efficacy of present practice we have utilized NNIS score and incidence of SSIs. Prospective observational study commenced in a major referral hospital. Patients previously on antibiotics were excluded from the study along with patients severely ill, NRC dirty wound category patients, Cancer Patients and patients with systemic infections. To evaluate efficiency of present practice SSIs incidence was analyzed using NNIS index score and its association with compliance with ASHP SAP guidelines. Overall surgical antibiotic prophylaxis (SAP) administration at study site was done in 96 cases (86.5%) out of all 111; in cases with no SAP administered 46.6% developed SSIs which is far greater than 7.2% cases where SAP was administered. In high risk patients (patients with NNIS score >1), Incidence of SSIs was seen greater than that in patients at lower risk patients with NNIS score ≤1. Full compliance with SAP guidelines comes with an ultimate benefit of reduction in incidence of SSIs which will lead to sure reduction in hospitalization due to SSIs and cost of therapy. Thus SAP administration should be compliant with evidence based recommendations to control emergence of SSIs in general surgery patients whether they are at high risk to develop SSIs or not.
Authors and Affiliations
Tarun Gautam1 , Ashwani Kumar2 , Sourabh Kosey1 , Harinder Pal Singh Sandhu2
Keywords
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