Are Biodegradable Third Generation Drug Eluting Stents the Answer to Instent Restenosis?
Journal Title: Cardiology and Angiology: An International Journal - Year 2014, Vol 2, Issue 1
Abstract
The third generation biodegradable Drug Eluting Stent (DES) are being evaluated and being introduced in clinical practice. They have been DESigned to overcome limitations associated with durable polymer and a persistent metallic stent scaffold which could be related to late target lesion revascularization (TLR) and very late stent thrombosis (VLST). Although a recent pooled data analysis found that biodegradable polymer stents were superior for TLR and VLST compared with first generation Sirolimus Eluting Stent (SES), superiority has not been demonstrated against second generation Everolimus eluting stents (EES) and is yet to be conclusively proven in randomized trials. This paper reviews the key features, recent trial data, and future directions of the third generation of DES technology including stents with fully biodegradable scaffolds, stents with biodegradable polymer, and polymer free stents.
Authors and Affiliations
Amod Amritphale, Nupur Amritphale, Chowdhury H. Ahsan
Keywords
Related Articles
- EP ID EP343934
- DOI 10.9734/CA/2014/9138
- Views 72
- Downloads 0
Early Detection of Abnormal Left Atrial and Left Ventricular Coupling, Using Two-dimensional Speckle Tracking Echocardiography in Patients with Preserved Left Ventricular Ejection Fraction
Aims: The aim of this study was to detect the abnormalities of left atrial (LA)-left ventricular (LV) coupling using two-dimensional speckle tracking echocardiography in patient with preserved LV ejection fraction. Meth...
Assessment of a Cardiac Rehabilitation Program Based on the Borg RPE Scale by Six-minute Walk Test: A Pilot Study
Aims: The ability of cardiac rehabilitation to reduce mortality in those with cardiovascular disease is well established. Despite its widespread use in the clinical setting, the Borg Rating of Perceived Exertion (RPE) sc...
Effect of Short Systemic Intermittent Hypoxia on Systemic Hemodynamics Blunted in Cutaneous Microcirculation
Background: Hypoxic stimulus induces a homeostatic disruption to enhance physiological adaptation. Blood flow in the microcirculation plays an important role in maintaining healthy tissues by delivering oxygen. The cutan...
Factors Influencing the Risk of Death among Patients with Heart Failure
The purpose of this study was to investigate the impact of risk factors on the death of patients with heart failure in a cohort of patients hospitalized with heart failure disease. In this paper we used chi-square tests...
Use of Levosimendan in Patients With Low Left Ventricular Ejection Fraction in Ordu/Turkey: Report of Experience with Mini Review
Aims:To report the effect of prophylactic usage of levosimendan in patients with low left ventricular ejection fraction undergoing coronary artery bypass grafting (CABG). Methods: We reported early results of 32 patients...