ARE THE SIDE EFFECTS OF PARACETAMOL BOOSTED BY CAFFEINE??

Journal Title: Journal of Drug Delivery and Therapeutics - Year 2017, Vol 7, Issue 2

Abstract

Paracetamol (acetaminophen) with caffeine is a combination medicine indicated for the temporary relief of pain and discomfort associated with a number of conditions such as headache or muscle pain. Paracetamol has a narrow safety margin and there are number of risks associated with paracetamol. It is only safe and effective when used according to directions on OTC (Over- The-Counter) and Rx labelling. However, long-term use of paracetamol increases the risk of kidney and liver failure and makes people more vulnerable to high blood pressure and strokes. Chronic or excessive administration of caffeine has been implicated in a range of dysfunctions involving the liver, renal system, gastrointestinal system, and musculature. A patient taking the combination of paracetamol with caffeine may be more likely to experience adverse effects than to get improved analgesia, compared with paracetamol alone.

Authors and Affiliations

Alla Seetha Devi

Keywords

Related Articles

“SOLID AS SOLVENT”: NOVEL SPECTROPHOTOMETRIC ANALYTICAL TECHNIQUE FOR QUANTITATIVE ESTIMATION OF TINIDAZOLE IN TABLETS USING SOLIDS (EUTECTIC LIQUID OF PHENOL AND LIGNOCAINE HYDROCHLORIDE) AS SOLUBILIZING AGENTS (MIXED SOLVENCY CONCEPT)

As per the mixed solvency concept, every substance present in this universe has got solubilizing power. The substance may be a gas, liquid or solid. The present research work is an attempt to demonstrate the solubilizing...

DOCKING, SYNTHESIS AND EVALUATION OF NOVEL DERIVATIVES OF SUBSTITUTED CHALCONES AS ANTIHYPERGLYCEMIC AGENTS

Various substituted chalcone derivatives (4A-4E) were synthesized. The structures of these compounds were established by spectral (IR, 1H-NMR, Mass) analysis. The synthesized compounds were screened for their antihypergl...

FORMULATION AND EVALUATION OF BILAYER TABLETS OF BACLOFEN USING SYNTHETIC POLYMERS

Aim of study was to develop bilayer drug delivery for treatment of spasticity by delivering loading and maintenance dose for fast achievement of peak plasma concentration and maintaining the same respectively. The prepar...

A ROLE OF MACROPHAGES: AN OVERVIEW

The macrophage is a type of phagocytic cell, which is a type of cell those are responsible for detecting, engulfing and destroying pathogens and apoptotic cells. Macrophages are produced through the differentiation of mo...

EXPLORATION OF ANTI-HYPERGLYCEMIC AND HYPOLIPIDEMIC ACTIVITIES OF ETHANOLIC EXTRACT OF TINOSPORA CARDIFOLIA (WILD)HOOK WHOLE PLANT IN ALLOXAN INDUCED DIABETIC RATS

Natural remedies from medicinal plants are considered to be effective and safe alternative treatment for diabetes mellitus. The aim of present study was to demonstrate the hypoglycemic and anti-diabetic activity of the E...

Download PDF file
  • EP ID EP294716
  • DOI 10.22270/jddt.v7i2.1388
  • Views 81
  • Downloads 0

How To Cite

Alla Seetha Devi (2017). ARE THE SIDE EFFECTS OF PARACETAMOL BOOSTED BY CAFFEINE??. Journal of Drug Delivery and Therapeutics, 7(2), 99-101. https://europub.co.uk/articles/-A-294716