Aspergillus flavus-Induced Brain Abscess in an Immunocompetent Child Case report
Journal Title: Sultan Qaboos University Medical Journal - Year 2016, Vol 16, Issue 2
Abstract
Intracranial aspergillosis is an extremely rare manifestation of invasive aspergillosis in immunocompetent children and is associated with high morbidity and mortality. We report a 12-year-old immunocompetent male child who was referred to the King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia, in May 2010 after a sudden-onset headache and loss of consciousness. Brain imaging revealed a large right space-occupying occipital lesion and the patient underwent a craniotomy and resection. Histopathology of the lesion revealed necrotising granulomatous fungal encephalitis with many hyphae engulfed by multinucleated giant histiocytes. Two days later, a computed tomography scan showed debulking of the fungal mass and the patient was discharged on oral voriconazole. However, imaging at a six-week follow-up showed progression of the abnormality. A residual or persistent fungal brain lesion was suspected. Further neurosurgical resection of the lesion was performed and cultures showed growth of Aspergillus flavus. Te patient was treated successfully with antifungal therapy over the following two years.
Authors and Affiliations
Nawal Al-Maskari| Department of Paediatric Infectious Disease, Royal Hospital, Muscat, Oman, Ibrahim Hussain| Departments of Child Health, King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia, Suleiman Jumaa| Departments of Paediatric Infectious Disease , King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia, Essam A. Al-Shail| Departments of Neurosurgery, King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia
Keywords
Related Articles
- EP ID EP14675
- DOI -
- Views 294
- Downloads 15
Bilateral Anterior Ischaemic Optic Neuropathy in a Child on Continuous Peritoneal Dialysis Case report and literature review
Non-arteritic anterior ischaemic optic neuropathy (NAION) is a serious complication of continuous peritoneal dialysis (CPD) which can lead to poor vision and blindness. We report a fve-year-old girl who had undergone a...
Porcelain Heart and Lung
‘Spoon-Fed’ Versus Self-Directed Learning in an Arab Context.
No Abstract
Spectrum of Paediatric Lysosomal Storage Disorders in Oman
Objectives: Te aim of this study was to look at the spectrum of paediatric lysosomal disorders in Oman. Lysosomal storage disorders (LSDs) are a heterogeneous group of inherited metabolic diseases. Few studies on the b...
Awareness of Breast Cancer Risk Factors, Symptoms and Breast Self-Examination Among Omani Female Teachers: A cross-sectional study
Objectives: This study aimed to assess knowledge of breast cancer (BC) risk factors, warning signs and symptoms and breast self-examination (BSE) practice among Omani female teachers in Al-Dhahira Governorate. Methods: A...