Assesment Of Antibacterial Activities Crude Leaf Extracts Of Selected Medicinal Plants From Ezza North Ebonyi State Nigeria Against Staphylococcus Aureus, Klebsiella Pneumoniae, Pseudomonas Aeruginosa. Escherichia Coli, And Streptococcus Mutans.
Journal Title: International Journal of Pharmaceutical Science Invention - Year 2017, Vol 6, Issue 9
Abstract
Aim :Medicinal plants have been used for ages as remedies for human diseases because they contain bioactive components of therapeutic value .This work was undertaken to investigate the in vitro antibacterial efficacy of six herbal extracts namely : Alstonia boonie,Morinda lucida, Parkia biglobosa,Olax subscopedia ,Anthocleista djolensis and Cusoniaspicataon six medicinally important bacterial strains (Klesbsiella spp, ,Staphylococcus, Streptococcus mutants, Pseudomonas aeruginosa,Salmonella spp, and E.coli ) . Method: Agar well diffusion method, with varying concentrations of each extract (100,50,25, and 12.5 mg/ml ) were used. Results : Alstonia boonei,showed no inhibition,Morindalucida showed maximum zone of inhibition against Klebsiella at 100mg/ml and 50mg/ml only, Parkia biglobosa exhibited inhibition from 25 mg/ml and maximum inhibitionwas recorded at 100mg/ml against E. coli,50 mg/ml against Staphylococcus whereas Cussoniaspicata showed maximum inhibition against E. coli and Pseudomonas at 100mg/ml only and no inhibition was observed against other isolates.Based on the present evaluationthis work suggest thatMorinda lucida,Parkia biglobosa,,Anthocleista adjolensis,and Cusonia spicata has inhibitory effects against some of the tested organisms and can be used in management of diseases caused by them while Alstonia boonie, and Olax may not be used. Conclusion: However, it may be inferred that these plants can be used as therapeutic natural agents that may serve as lead for development of new pharmaceuticals addressing the major therapeutic needs.
Authors and Affiliations
ALI FREDRICK U, ORINYA O. F, OMINYI M. C, EZENWALI M. O. , ONWE L. C. , NWACHETA C. , ALIEGBERE A. , AKPAN M. S. , NWITE O. M. , ONUIGBO G. N
Keywords
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