Assessment of a diagnostic value of histopathological test results in miscarriages, depending on a treatment method applied
Journal Title: Ginekologia i Położnictwo medical project - Year 2017, Vol 2, Issue 44
Abstract
Introduction. The miscarriage rate among patients who know they are pregnant, is roughly 10 to 15%. An empty gestational sac or a missed or incomplete abortion are all indications for either invasive or pharmacological treatment. In the process uterine products of conception are being examined by histopathologic. The aim of this study was to determine the diagnostic value of miscarriage tissue acquired as the result of either pharmacological or invasive treatment. Material and methods. In this retrospective study we analysed history of 258 patients hospitalised in 2016 within the 2nd Dept. of Obstetrics and Gynaecology, Wroclaw Medical University, with an initial diagnosis of missed abortion or empty gestational sac. We compared the diagnostic value of histopathological reports on the uterine products of conception collected either after pharmacological treatment or after invasive curettage. We analysed collected data using statistical models. Results. Among the analysed patients 232 (92,6%) underwent pharmacological treatment which was the only treatment resulting in completion of miscarriage in 61 patients (23,7%), versus 171 patients (68,9%) who were qualified for curettage of the uterine cavity due to insufficient emptying of the uterine cavity after pharmacological treatment. 16 (6,2%) patients underwent curettage without previous pharmacological treatment. Uterine products consisting of both fetal and maternal tissue has been obtained in 80 cases (35%) after only pharmacological treatment vs in 133 (52%) after curettage. Nondiagnostic histopathological material was observed in 38 patients (15%) after only pharmacological treatment vs in 6 patients (2%) after curettage. Observed differences were statistically significant. Conclusions. Pharmacological treatment of miscarriages has many advantages but it does not guarantee to provide diagnostic material for future histopathological analysis. In all cases of insufficient emptying of the uterine cavity, the invasive approach - curettage - should be advised in order to obtain good quality tissue samples for histopathological analysis.
Authors and Affiliations
Jakub Śliwa, Anna Kryza-Ottou, Artur wiatrowski, Paulina Luty, Mateusz Sobalak, Aleksandra Zimmer, Mariusz Zimmer, Maciej Kaczorowski
Keywords
Related Articles
- EP ID EP555053
- DOI -
- Views 166
- Downloads 0
Hormonal changes in perimenopausal women
Introduction. Premenopausal syndrome is a neurohormonal disorder characterized by general, mental and somatic symptoms. Aim. Assessment of serum levels of: follicle-stimulating hormone (FSH), luteinizing hormone (LH), es...
Zawodowa jakość życia polskich ginekologów i położników
Wstęp. Wypaleniem zawodowym określa się stan wyczerpania emocjonalnego, depersonalizacji i obniżonego poczucia dokonań osobistych. Grupa ryzyka narażona na wystąpienie wypalenia to osoby zawodowo świadczące pomoc innym,...
Niepełnoletnia ciężarna – medyczne i prawne aspekty
Wstęp. W języku potocznym dla określenia pacjentki niepełnoletniej, czyli takiej która nie ukończyła 18 lat intuicyjnie używamy zamiennie kilku pojęć: nieletnia, małoletnia i młodociana. W języku prawniczym te określenia...
Request for caesarean section – should it be combined with anxiety and depression?
Introduction. The number of pregnancies terminated by a Cesarean section (CS) has been rising in Poland for many years. This increase is particularly evident in the group of operations conducted for indications other tha...
Depression and anxiety during pregnancy as risk factors for preterm labour and low birth weight
Although the postnatal depression is a well-studied and described in the medical literature, much less is known about the antenatal depression. Meanwhile, studies show that approximately twelve percent of women experie...