Assessment of Adverse Drug Reaction’s From The Treatment Charts of A Hospitalised Patients Suffering With Cardiac Arrhythmias And Complications Due To Adverse Drug Reaction’s
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 4
Abstract
Cardiac Arrhythmia is a condition in which the heart’s normal rhythm is disrupted. The heart may beat too slowly, too quickly or with an irregular rhythm. Most arrhythmias are harmless, but some can be serious and potentially fatal. Disturbed heart rhythms can restrict blood being pumped around the body, which may cause damage to the brain, heart and other organs. Common causes of arrhythmia are stress, caffeine, tobacco, alcohol, diet pills and cough and cold medicines. Adverse drug reaction is defined as "an appreciably harmful or unpleasant reaction, resulting from an intervention related to the use of a medicinal product, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. "Materials and Methods: Study design: This study was a prospective observational study conducted in tertiary care hospital. Study population: The study was done in the patients of intensive care unit and acute medical care unit who are suffering with cardiac arrhythmias and complication of anti-arrhythmic drugs. Study procedure: The data is collected from the patients with patient profile form and patient consent form. Study duration: The study was conducted for 4 months i.e. from December 2017 to March 2018. Study material: Patient consent form: Consent was collected by using self designed patient consent form and consent was made into three languages English, Telugu, Hindi. Ethical approval: The study was approved by institutional ethical committee and tertiary care hospital committee, which has followed all the guidelines of the committee. Results: Out of 132 patients 90 are willing to give information of the condition and tabulated. Discussions: Out of 132 patients 90 patients are willing to give information out of which male and females are more and age group of 55-60 suffered more. Maximum people with education level are tertiary and the reason for developing arrhythmias is due to complications of cardio vascular disease. Symptoms developed were fluttering chest pain, tachycardia, bradycardia and chest pain, loss of appetite and the different classes of antiarrhythmic drugs prescribed for cardiac arrhythmias are mainly beta blockers and calcium channel blockers. The Comorbidity conditions of the patients were hypertension, diabetes mellitus, hyperthyroidism most of the ADR’s are treated with different classes of drugs. Conclusions: Adverse drug reactions are avoidable cause of patients harm. Findings obtained in the present study revealed that there is significant number of adverse drug reactions. The most commonly ADR’s are Chest pain, hypotension, Nausea, diaphoresis, Headache, fatigue, weakness, dizziness. Improving the coverage and accuracy of adverse drug reactions can improve delivery of safe and cost effective patient care. Understanding the mechanism of adverse drug reaction will assist all the clinicians in avoiding these serious, often preventable events. Clinical Pharmacist should play a key role in monitoring the adverse drug reactions, drug interactions, current medication charts of the patients.
Authors and Affiliations
Dr. Kanamala Arun Chand Roby, Ayesha Tazeen, Thungapendi Swaraj
Keywords
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- EP ID EP370511
- DOI 10.9790/0853-1704046576.
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