Assessment of effectiveness of prophylactic topical antibiotic visa-vis oral antibiotic in the prevention of surgical site infection in elective open inguinal hernioplasty
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 6
Abstract
Background: Reports in literature are conflicting with regard to the necessicity and effictiveness of antibiotic prophylaxis in inguinal hernia repair surgery. However, antibiotic prophylaxis is used in many centers as placement of a prosthesis (mesh) would lead to serious consequence should infection occur. Intravenous route is the most common mode of administration, but orally administered antibiotic and topical antibiotic application for prophylaxis are also used. Intravenous administration is associated with much more severe adverse effects and economic liability as compared to oral or topical prophylactic methods. Aim of the study : To assess the effectiveness and compare the degree of prophylaxis between pre-operative orally administered ciprofloxacin (500 mg) and intra-operative topical application of ciprofloxacin solution (200 mg) as methods of prophylaxis against surgical site infection in elective Lichtenstein inguinal hernia repair. Material and method : This is a prospective single-blind randomized study consisting of a total of 212 patients conducted over a period of four years at a tertiary care center in north eastern India. Eligible patients were allocated to two treatment arms, one group of patients (n = 107) received oral ciprofloxacin 500 mg preoperatively and another group (n = 105) received topical ciporfloxacin delivered locally to the wound. Demographic data and relevant parameters were collated and analyzed at the end of a one year follow up period. Results : Both orally administered ciprofloxacin and topically delivered ciprofloxacin appeared to be equvalent in efficacy and confer a similar degree of prophylaxis against surgical site infection in elective Lichtenstein inguinal hernia repair.
Authors and Affiliations
Khongwar D, Tongper D, Topno N, Hajong R, Baruah A J, Komut O, Saikia J, Anand M
Keywords
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- EP ID EP376649
- DOI 10.9790/0853-1706103342.
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