ASSESSMENT OF INFLUENCE OF METABOLIC SYNDROME ON HEART FAILURE
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2019, Vol 6, Issue 33
Abstract
BACKGROUND Many recent literature reveals a rapid escalation of this metabolic syndrome (METS) specially insulin resistance among Indians and the prevalence of predominant component of METS varies among region.1 The increased risk of morbidity and mortality associated with the METS makes it essential that there is a clear understanding of the dimensions of this syndrome for the allocation of health care and research resources and for other purposes.2 Hence, the present study was undertaken to assess the influence of metabolic syndrome on heart failure. METHODS This is a prospective hospital-based study carried among patients with acute myocardial infarction during November 2009 to March 2011. Sample size was calculated using the formula n=4pq/L2. Hence 92 patients with acute myocardial infarction were enrolled in this study. Statistical analysis was done using SPSS 20. Results were presented as percentage, mean and standard deviation (SD). RESULTS The age of the patients ranged from 21 to 90 years, with a median age of 55 years. Maximum number of cases was in the 51- 65 years age group (47.9%). Male cases predominated in both the groups with and without metabolic syndrome (61.4% and 72.2% respectively). ST-elevation myocardial infarction was present in 80.21% of metabolic syndrome patients. Among the components of metabolic syndrome, low HDL cholesterol was the most prevalent component in both the groups. High fasting blood sugar or diabetes (89.5%) was the next most prevalent component in metabolic syndrome cases followed by hypertension or blood. CONCLUSIONS Development of complications in acute myocardial infarction was around 4 times higher in metabolic syndrome patients compared to cases without metabolic syndrome.
Authors and Affiliations
Archana M. Uppin, Raju H. Badiger, Soumya Parne, Indu Yadav, Shreekant Chowdary, Pawan Kumar M. , Sreedhar J. , Rishabh A
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