Assessment of Myocardial Perfusion Scan in the Detection of Ischemia and Accurately Measuring the Ejection Fraction in CAD Patients in Western Saudi Arabia: A Retrospective Cohort Study
Journal Title: International Journal of Medical Research Professionals - Year 2018, Vol 4, Issue 6
Abstract
Background: Cardiovascular diseases are one of the most common diseases in Saudi Arabia and one of the most common leading causes of death. Myocardial perfusion scan (MPI) is one of the most commonly used imaging techniques for detection of myocardial ischemia and cardiac tissue viability. Previous literature estimated that the sensitivity of MPI in detecting the diseased patients ranges from 67-79 % and with specificity that ranges between 74-83%. Such assessments of MPI perfusion and ejection fraction evaluation have not been proven or estimated in our population and with the wide use of MPI in our country, it is important that new assessments should be conducted. Methods: The records of King Abdullah Medical City were searched to locate the files of 535 cardiac patients who had undergone MPI. For all patients, the following data were extracted: demographics, co-morbidities, MPI results, coronary angiography results, and echocardiography results. After collecting all the data, sensitivity, specificity, positive predictive value, and negative predictive value were calculated. For ejection fraction, the level of agreement was examined between both MPI and echocardiography EF results. Results: Analysis included 531 patients, 340 males and 191 females, with a mean age of 59.94 years. 319 patients had diabetes, 363 were hypertensive, and 227 had dyslipidemia. MPI had a sensitivity of 91.8% and a specificity of 23.08%, with a positive predictive value of 71.63% and negative predictive value of 57.14%. Kappa measure of agreement between the ejection fraction of MPI and echocardiography showed a statistically significant difference (P<0.001) and k=0.376. Conclusion: MPI has high sensitivity but low specificity in detecting coronary artery disease, and not reliable in measuring EF in CAD patients.
Authors and Affiliations
Marwan Albeshri, Loay Khair, Soha Elmorsy, Bashair Melebari, Mohammed Alsallum, Anas Alsolami, Abdalrhman Qazli, Anwar Melebari, Fatma Aboul-Enein
Keywords
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- EP ID EP532398
- DOI 10.21276/ijmrp.2018.4.6.005
- Views 61
- Downloads 0
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