Assessment of Sentinel Nodes with Methylene Blue Dye in Carcinoma Breast is Feasible? A Pilot Study
Journal Title: INTERNATIONAL JOURNAL OF SCIENTIFIC STUDY - Year 2017, Vol 5, Issue 1
Abstract
Introduction: Management of axilla is an integral part of treatment of carcinoma breast. Axillary lymph node dissection has a well-established role in regional disease control and it provides information about the histopathological status which has significant prognostic and therapeutic implications. Materials and Methods: Thirty five patients with breast cancers with stages T1-T3, N0, and one patient with T3 N1 M0 disease who had become node negative post chemo therapy were included in the study. 5 patients with breast cancer clinically node negative axilla were excluded from the study after they have found to have axillary nodes after ultrasound examination. Totally 36 patients were evaluated. Results: This study demonstrates that sentinel node localization is possible with methylene blue dye alone with 88.88% localisation rate. Though limited by small sample size this study has shown a low false negative rate of 6.25%. which denotes that SLN biopsy using methylene blue dye alone is a highly reliable and predictable technique to stage the axilla in breast cancer patients. Conclusion: This technique may help to avoid complete axillary lymph node dissection in sentinel node negative patients thereby minimising the morbidity of axillary lymph node dissection.
Authors and Affiliations
J Sakthi Ushadevi
Keywords
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