Assessment of Serum Magnesium Levels in Stroke Patients and its Correlation with Severity of Neurological Disability
Journal Title: International Journal of Contemporary Medical Research - Year 2018, Vol 5, Issue 5
Abstract
Introduction: WHO clinically defines a stroke as ‘the rapid development of clinical signs and symptoms of a focal neurological disturbance lasting more than 24 hours or leading to death with no apparent cause other than vascular origin’. Magnesium may play a preventive and therapeutic role in stroke, ischemic heart disease, and bronchial asthma. Aims and Objectives: To determine the levels of serum magnesium, evaluate the neurological status and to compare and explore the difference in serum magnesium levels in ischaemic and haemorrhagic stroke. Material and methods: The present study was conducted in the Department of medicine, Pt. J.N.M. Medical College and Dr. B.R.A.M. Hospital, Raipur (C.G.). Total 60 subjects including 30 stroke patients and 30 normal Individuals aged between 18-60 years of both sexes were included in the study. Age and Sex matched subjects were taken for the normal control group. Results: Highest incidence of stroke was observed in 51- 60 years of age group (mean age 51.10±14.74 years), 60% are male (n= 18), unconsciousness was present significantly (p=0.002*) higher frequency in Stroke group, and infract was the most common type of stroke (n= 23, 76.7%) observed. Sr. mg levels were significantly lower in stroke subjects and in subjects with mRS 3-6 compared to control subjects (p<0.0001*) and those with mRS 0-2 (p=0.004*). Systolic BP was significantly higher in stroke subjects (p=0.004*). mRS score was significantly lower in infarct subjects compared to hemorrhagic stroke subjects (p=0.003*). Conclusion: Cerebrovascular disease predominates in the middle and later years of life. Men are more prone to thromboembolic stroke. Magnesium levels are significantly decreased in ischaemic stroke, though haemorrhagic stroke patients had a magnesium deficiency
Authors and Affiliations
R. K. Patel, Devendra Kumar Sahu, Swarna Gupta
Keywords
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