Assessment of Serum Zinc among Sudanese Patients with Acute Myocardial Infarction
Journal Title: Journal of Advanced Medical and Dental Sciences Research - Year 2018, Vol 6, Issue 9
Abstract
Background: AMI is one of the leading causes of morbidity and mortality across the world. Zinc is important trace element and has important role as antioxidant element and cell membrane stability and there is paucity of information in the literature in this regard ;so this study was done to assess serum level of zinc in cases of AMI in Khartoum state. Objective: The aim of this study is to assess the level of serum zinc in patients with acute myocardial infarction an its correlation with cardiac markers. Materials and Methods: this study was performed at Sudan Center for Heart disease in Khartoum state , Sudan, during the period from February to October 2017.50 sample were collected from admitted patients with acute myocardial infarction as test group, in addition to other 50 sample from healthy volunteer sex and age matched as control group . the levels of serum zinc element were determined in both group by atomic absorption spectroscopy. Results: serum zinc levels were significantly lower in patients with acute myocardial infarction when compared with control group (0.351±0.08 versus 0.531±0.09, p = 0.000) in table 1.According to age groups of the test group there is insignificant difference in serum zinc and troponin T levels ( P > 0.05) .Whereas across duration of infarction serum zinc level is significantly decreased in day 1(0.35 ± 0.08 versus 0.53 ±0.09, p = 0.000), day 2 (0.31± 0.05 versus 0.53 ±0.09, p = 0.000), and started to increase in day 3( 0.39 ± 0.09 versus 0.53 ±0.09, p = 0.01), and serum zinc fluctuated to normal level in day 10 (0.50 ± 0.06 versus 0.53 ±0.09, p = 0.91) . The study observed insignificantly inversely correlated between serum zinc level with AST and LDH ( P > 0.05).But significant inversely correlation with with serum CKMB and troponin T(r= - 0.28. p= 0.03and -r = 0.34,p = 0.001respectively). Conclusion: The study revealed reduced serum zinc level in patients with acute myocardial infarction, and significantly inversely correlated with cardiac markers CKMB and troponin T.
Authors and Affiliations
Hozifa abed albage yousif, Abdelmula M. Abdalla
Keywords
Related Articles
- EP ID EP549418
- DOI -
- Views 108
- Downloads 0
Assessment of Efficacy of two Different Obturating Techniques while performing Root Canal Therapy: A Comparative Study
Background: The success of this treatment depends on many factors, and the technical quality of Root canal therapy is one of the most important.The success features of RCT, namely absence of pain, regression of AP, tight...
Comparative Assessment and Evaluation of Shear Bond Strength of Resin-Bonded Fixed Partial Restorations as affected by Diamond Rotary Burs with Different Grit Sizes- An in vitro study
Aim: The resistance and retention forms as the determining factors affecting the success of retention of resin-bonded restorations. The present study was conducted to compare the effects of diamond rotary burs with diffe...
Correlation of Salivary Glucose and Blood Glucose Level in Diabetes Patients - A Clinical Study
Background: The estimation of diabetes mellitus may be done with blood investigations. Saliva is only one of its kind and curiosity in it as a diagnostic media has vastly developed. The present study was conducted to cor...
A Comparative Study of Level of Anxiety and Depression among Adolescents aged between 13-19 Years
Background: Mental disorders are among the most burdensome of all classes of disease because of their high prevalence, chronicity, early age of onset and resulting serious impairment and disability. Failure to adjust wi...
Expression of Podoplanin in Odontogenic Keratocyst: An Immunohistochemical Study
Background: The odontogenic keratocyst (OKC) is known to have a more aggressive biologic behaviour than other cysts of jaw. Podoplanin which is frequently used as a lymphatic endothelial marker in OSCCs has recently been...