Assessment of Vascular Age in Asymptomatic Persons in Indian Population
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2018, Vol 6, Issue 12
Abstract
Abstract: The Concept of vascular age (Age of arteries) is a concept related to cardiovascular risk that might be more easily understood by all patients. This study aimed to evaluate whether vascular age is advanced as matched to their chronological age in apparently healthy, asymptomatic population and to assess the contributing risk factors for premature vascular ageing. Hospital based, observational study of 547 individuals conducted from May 2015 to December 2017. Persons enrolled were asymptomatic with normal ECG, chest X-RAY and ECHO and were drug free. Population enrolled were monitored by regular visit and telephonically for the events. The vascular age of the population was calculated using Framingham vascular age calculator. Statistical analyses were done using SPSS software V 20.0. The cut off value of P < 0.05 was considered statistically significant. RESULTS: The mean chronological age of the study population was 53.92+/- 14.86 years whereas mean vascular age was 63.55+/-15.51 years, and the difference 9.87+/-11.05 between both was statistically significant (P < 0.001). Contributory risk factors for advanced vascular age apart from chronological age were smoking, diabetes, Low HDL, Total cholesterol/HDL ratio and systolic blood pressure. Results of regression analysis showed that vascular age progression was highly associated with, Age 1.059 (C.I 1.016 to 1.105) P=0.007, SBP 1.045 (C.I 1.018 to 1.072), P=0.001, Smoking 2.657(C.I 1.177to6.000) p=0.019, Diabetes mellitus.1.84 (CI 0.876 to0.958) p= 0.05 and Triglyceride 1.010(1.004to1.016) p=.001.CONCLUSIONS: Significant difference was observed between chronological and vascular age, so routine screening for vascular age and risk factors (specially lipid profile and blood pressure measurement) is strongly advocated for asymptomatic relatives of patients with IHD.
Authors and Affiliations
Ram Sagar Roy, Anita Kumari, Shashikant . , Rajendra Kumar Gokhroo
Keywords
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