Association between chronic kidney disease and plasma homocysteine level - A hospital based study
Journal Title: Medpulse International Journal of Medicine - Year 2019, Vol 9, Issue 1
Abstract
Background: Chronic kidney disease (CKD) is known to cause hyperhomocysteinemia which contributes to increased cardiovascular morbidity and mortalities. Hence the study aimed to find the homocysteine level in patients with chronic kidney disease. Material and methods: 50 patients with CKD were recruited in the study, and their fasting plasma homocysteine level was measured. Normal plasma homocysteine level was considered to be below 15 µmol/litre. Observations and Results: Of 50 patients (Males: 37, females: 13 Age range: 41-60), 36 patients had stage 5 CKD. Hyperhomocysteinemia was observed in 78% of CKD patients. 94.87% had mild hyperhomocysteinemia. End-stage renal disease patients had increased prevalence of hyperhomocysteinemia. No significant difference was found in hyperhomocysteinemia state between patients undergoing dialysis and without dialysis. Conclusion: Hyperhomocysteinemia is a highly prevalent condition seen in CKD patients.
Authors and Affiliations
S Manoharan, G K Adarsha, M Natesh Prabhu
Keywords
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- EP ID EP517582
- DOI 10.26611/10219116
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