Association between polymorphism in STAT5A gene and milk production traits in Chinese Holstein cattle
Journal Title: Animal Science Papers and Reports - Year 2010, Vol 28, Issue 1
Abstract
STAT5 is a key intracellular mediator of prolactin signaling and can activate transcription of milk proteins in response to prolactin. STAT5 genes are suggested to be candidate markers for milk protein yield and composition in dairy cattle. PCR-SSCP was applied to analyze the polymorphisms of two loci in STAT5A gene in 279 Chinese Holstein cattle. Genotype frequencies, allele frequencies and correlation coefficients between the polymorphic variants and milk production traits were estimated. Three genotypes were found at the two loci. At locus P1 the frequencies of genotypes AA/GG/AG were 0.240/0.147/0.613 and those of alleles A and G were 0.547 and 0.453, respectively. The A/G genotypes had significant effect on milk yield and milk protein content in lactations 1 and 2. At locus P2 the genotype frequencies of CC/TT/CT were 0.752/0.004/0.244 and C and T allele frequencies were 0.875 and 0.125, respectively. Different genotypes had remarkable effect on the milk protein content in lactation 2.
Authors and Affiliations
Bin Bao, Chunlei Zhang, Runfeng Zhang, Chuanwen Gu, Chuzhao Lei, Hong Chen
Keywords
Related Articles
- EP ID EP71352
- DOI -
- Views 132
- Downloads 0
Effect of dietary mixture of Aspergillus probiotic and selenium nano-particles on growth, nutrient digestibilities, selected blood parameters and muscle fatty acid profile in broiler chickens
Forty five chickens (15 days old) were assigned to three groups: (1) control group fed a basal diet; group (2) fed the basal diet supplemented with 0.05% Aspergillus awamori and group (3) fed mixture of A. awamori 0.05%...
Power of different microsatellite panels for paternity analysis in sheep
The aim of this work was to develop and to test PCR-based suitable microsatellite marker panels for paternity testing in sheep. Blood samples were collected from 212 Kivircik sheep (24 rams and their 188 offspring) rais...
Effect of dietary selenium and vitamin E on chemical and fatty acid composition of goose meat and liver
The effect of dietary supplementation with organic selenium and vitamin E on chemical characteristics and fatty acid composition of goose meat (breast and leg muscles) and liver is described. Two-hundred one-day-old Whit...
A well-known mutation in RYR1 alters distribution of adipose tissue in gilts
The swine RYR1 (ryanodine receptor 1) gene is a major gene for meatiness, but its effect on the fatness and location of fat deposition is less known. A known mutation in this gene is responsible for a drastic deteriorati...
The effect of gamma irradiation and vacuum packaging upon selected quality traits of refrigerated ostrich meat. Part 1. Microbial assessment
The aim of the study was to evaluate the effects of gamma irradiation and vacuum packaging as combined process for improvement of ostrich meat shelf life. Ostrich meat was vacuum-packaged and irradiated at 0, 1 and 3.0 k...