Association between Thyroid Dysfunction during Early Pregnancy and its Correlation with Lipid Abnormalities - A Cross-Sectional Study
Journal Title: International Journal of Contemporary Medical Research - Year 2018, Vol 5, Issue 6
Abstract
Introduction: Thyroid disease is the second most common endocrine disorder affecting women of reproductive age and when left untreated during pregnancy is seen with an adverse risk of placental abruption, anaemia in pregnancy, miscarriages, hypertensive disorders and growth restriction. During pregnancy, thyroid gland regulates the production of hormones called triiodothyronine (T3) and thyroxine (T4) which plays an important function in the development of the brain and nervous system of the foetus. The aim of the present study is to assess the association between maternal lipid profile and thyroid stimulating hormone in pregnancy. Materials and methods: The present study was performed in department of physiology. Out of which 100 antenatal cases from October, 2015 to October 2017 were enrolled after taking an informed written consent. The venous blood sample was collected from all subjects for measurement of lipid profile and thyroid hormones in the 16th week and 32nd week of gestation for analysis. Results: It was observed that T3, T4, TSH were increased significantly among healthy pregnant women. Significant positive correlation was seen between TSH and Triglycerides and also between T3 and Cholesterol. Conclusion: Screening for lipid profile and thyroid hormone in pregnant women is essential to prevent medical complications during pregnancy.
Authors and Affiliations
Krishna Kumari, Siyavar Sharan, Rajendra Kumar
Keywords
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