Association of ABO blood groups and Von Willebrand Factoramong Sudanese individual in Khartoum Sudan
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 3
Abstract
Background: Von Willebrand factor (VWF) is a large adhesive glycoprotein synthesized by endothelial cells and megakaryocytes. The antigens of the ABO system (A, B, and H determinants, respectively) consist of complex carbohydrate molecules.ABO blood group locus on chromosome 9q34exert major quantitative effects on VWF level. Objective: The purpose of this study was toevaluate the association of Different ABO blood groups and VWF level among Sudanese Subjects. Materials and Methods:Eighty-two samples were included in this study, Von Willebrand factor levels were determined among various blood groups. VWF was determined using ELISA method and Blood group was determined by using direct blood group method. Results: The males were 56 (68%) and Females were 26 (32%). The frequencies of different blood groups were as follows: AB 10 (12.2%), A 21 (25.6%), B 12 (14.6%) and O 39 (47.6). VWF levelswere significantly higher in non-group O than group O individuals. Conclusion: This study has concluded that VWF: Ag level is higher in non-group O than in group O individuals.
Authors and Affiliations
Mohamed Abdallabakheit eltaher, Mahdi H. A. Abdalla
Keywords
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- EP ID EP600195
- DOI 10.9790/0853-160309103106.
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