Association of ABO Blood Groups with Cardiovascular Diseases in Adult Indian Population
Journal Title: JOURNAL OF PHARMACEUTICAL TECHNOLOGY, RESEARCH AND MANAGEMENT - Year 2013, Vol 1, Issue 2
Abstract
This study was designed to investigate whether there was an association between ABO blood groups and major cardiovascular diseases (ischemic heart diseases) in adult Indian population. The present retrospective study analyzed ABO blood groups among 1527 patients with documented IHD, who were treated at CIMS Hospital in Ahmedabad city from January to December, 2011 comparing with a control group of 860 subjects. Data were analyzed with GraphPad Prism 6.0 and by using chi square test. A p-value less than 0.05 were considered as +statistically significant. No significant difference in distribution of ABO blood groups was seen in patients with IHD (A, 21.95%; B, 35.41%; AB, 8.61%; O, 34.01%) and also after adjustment for common cardiovascular risk factors such as age, gender, addiction history, obesity, hypertension, diabetes in these patients (A, 25.47%; B, 37.53%; AB, 9.04%; O, 27.94%) as compared to the controls (A, 22.32%; B, 35.58%; AB, 8.83%; O, 33.25%), p-value = 0.9916 and 0.2778 respectively. The findings of the study suggest that there seems to be no correlation between various ABO blood groups and development of cardiovascular diseases. Moreover, the prevalence of major risk factors was equal in patients with different blood groups and blood groups had no impact on development of cardiovascular pathogenesis in individual subjects.
Authors and Affiliations
Pooja Sahita , Indermeet Singh Anand , Manisha Shah
Keywords
Related Articles
- EP ID EP596677
- DOI 10.15415/jptrm.2013.12011
- Views 210
- Downloads 0
Preparation and Characterization of Phytosomal-Phospholipid Complex of P. Amarus and its Tablet Formulation
Present investigation was aimed at formulation, characterization and evaluation of phytosomal complex tablets for sustained delivery of Phyllanthus amarus complex. Phyllanthin, one of the active lignin present in this pl...
An Update on Some Recent Solubility Enhancers as Pharmaceutical Excipients
At present the pharmaceutical academia and industries are focusing on the use of natural materials and resources for development of pharmaceutical product. Due to advances in drug delivery technology, currently, excipien...
Standardization of Some Commercial Anti-diabetic Herbal Products containing Syzygiumcumini
An isocratic HPLC method was developed for standardization of five commercially available products containing S. cumini seeds (DIABECON, MADHULENE, HYPONIDD, D-FIT and DIABEGON)using methylxanthoxylin (MXX)as marker. The...
Histone Deacetylase Inhibitors As Potential Therapeutic Agents For Various Disorders
Epigenetic modification acetylation or deacetylation of histone considered as an important element in various disorders. Histone acetyltransferases (HATs) and histone deacetylases (HDACs) are the enzymes which catalyse t...
Pharmacognostic Standardization of Biophytum Sensitivum Dc
Biophytum sensitivum DC. (Family – Oxalidaceae) is a traditional drug used in treating various ailments especially in mental disorders. The present study was envisaged to establish pharmacognostic standards of the plant...