ASSOCIATION OF ABO BLOOD GROUPS WITH DIABETES MELLITUS
Journal Title: International Journal of Basic and Applied Physiology - Year 2016, Vol 5, Issue 1
Abstract
Background & objectives – Diabetes mellitus(DM) is multifactorial disease, aetiology of diabetes is complex and involve genetic aspect, Blood group antigens are also hereditary determined and plays a vital role in to understand genetics, inheritance pattern, and disease susceptibility.The rationale behind this study was that there might be an association between the ABO blood group and diabetes mellitus and based on result we can identify the susceptible and adopt some preventive measures to decrease the burden of disease in society.Materials and Methods–a cross sectional study was performed on 120 patients suffering from diabetes mellitus had taken detailed history, informed consent and ABO Blood group collected from database, against randomly selected 660 people in the control group who were registered blood donors, not suffering from diabetes mellitus in blood bank of government hospital to find out prevalence of blood group in local population. Appropriate statistical test applied on collected data. Result– odds ratio showed there was high relative risk in Blood group B as compare to blood group O & A, however chi-square test does not show there is significant association between ABO Blood group and diabetes mellitus. Interpretation & conclusion. – from this study we can conclude that Blood group B persons having high relative risk for developing DM, compared to other ABO blood groups, however large scale study required to find out further association
Authors and Affiliations
Dharmendra Dodiya, Anup Patel, J. M. Jadeja
Keywords
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