Association of Glycated Hemoglobin (HbA1c) with Coronary Artery Disease In Non-Diabetic Patients: An Institutional Based Study
Journal Title: International Journal of Medical Research Professionals - Year 2018, Vol 4, Issue 3
Abstract
Background: Elevated glycosylated hemoglobin A1c (HbA1c) is associated with increased risk of atherosclerosis and cardiovascular mortality in diabetic patients. In the present study, we examined the association between HbA1c and presence of angiographically proven coronary artery disease (CAD), its severity and complexity in non-diabetic subjects. Materials & Methods: A Hospital based Observational Study done on 300 patients in Department of Medicine & Department of Pathology in S. P. Medical College & associated group of hospitals at Bikaner, Rajasthan. Assessment of the severity of coronary artery disease was done using Gensini score. Results: Among total number of 150 screened patients as non -diabetics, 10 patients were excluded as fasting blood sugar > 126mg/dl or HbA1c more than 6.5%, 5 patients were excluded because no evidence of CAD. Among 135 patients included, male gender pre dominated (81.48%). Most of patients were overweight with mean BMI = 27.5±4.9.The most common cause of performing coronary angiography was unstable angina (45.18%). The Gensini score ranged from (1 to 168) with a mean of 33.95 ± 32.9. 100 patients were in high risk group with (HbA1c 5.7 – 6.4%) while only 35 patients were in low risk group with (HbA1c <5.7%). Conclusion: We concluded that HbA1c level is a useful marker and has a prognostic value to predict the severity of CAD among non-diabetic patients.
Authors and Affiliations
Mahesh Pal Khatri, Vijayta Modi
Keywords
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- EP ID EP531980
- DOI 10.21276/ijmrp.2018.4.3.036
- Views 78
- Downloads 0
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