ASSOCIATION OF IN-HOSPITAL OUTCOME OF ACUTE KIDNEY INJURY (AKI) WITH ETIOLOGY AMONG NEWBORNS AT A TERTIARY CARE UNIT
Journal Title: World Journal of Pharmaceutical and Medical Research - Year 2018, Vol 4, Issue 3
Abstract
Objective: To determine association of in-hospital outcome of AKI with etiology in newborns at a tertiary care hospital. Methods: This descriptive cross-sectional study was conducted at Department of Pediatric Neonatology, DHQ teaching hospital, Sargodha by using non-probability purposive sampling technique from June 2016 to June 2017. A total of 101 newborns diagnosed with acute kidney injury were registered. Etiological factors were assessed and these patients were followed till discharge to monitor in-hospital outcomes. Results: Of these 101 newborns, 75 (74.3%) were boys while 26 (25.7%) were girls. Mean age of these newborns was 7.59 ± 6.13 days (range; 1 day to 28 days). Mean age of the boys was 5.73 ± 7.20 days while that of girls was 6.77 ± 6.16 days. (p=0.515). Mean weight of these neonates was 2545.05 ± 600.42 grams (range; 1000 grams to 4000 grams). Mean serum potassium level was 4.94 ± 0.92 mgEq/L ranging from 3.1 mgEq/L to 7.0 mgEq/L. Mean urea level was 73.35 ± 27.65 mg/dl ranging from 18 mg/dl to 206 mg/ dl. Mean serum creatinine level was 1.98 ± 0.27 mg/dl, ranging from 1.6 mg/dl to 2.8 mg/dl. Mean serum sodium level was 145.72 ± 12.64 mgEq/L ranging from 126 to 166 mEq/L. Eighty one (80.2%) were term babies while 20 (19.8%) were pre-term babies. Of these 101 study cases, 29 (28.7%) delivered vaginally while 72 (71.3%) through cesarean section. Delayed crying was noted in 48 (47.5%), dehydration 13 (12.9%), sepsis in 36 (35.6%) and renal malformation in only 4%. Neonatal mortality in these patients was 15 (14.9%) while 86 (85.1%) were discharged from hospital after recovery. Conclusion: Acute kidney disease in newborns is associated with significant disease morbidity and mortality with asphyxia and sepsis are the main etiological factors responsible. It is predominantly more common in boys compared with girls. Mortality rate was high in our study and it was significantly associated with female gender. Mortality was also associated with elevated serum sodium and urea level.
Authors and Affiliations
Dr. Arsalan Nasir
Keywords
Related Articles
- EP ID EP658943
- DOI -
- Views 160
- Downloads 0
TUBERCULOSIS IN ICU PATIENTS
Introduction: Tuberculosis (TB) is an infectious disease that causes significant mortality and morbidity worldwide.There are still many questions about the diagnosis of TB. In this study, we evaluated the clinical and la...
PROGNOSTIC ROLE OF HUMAN PAPILLOMA VIRUS IN ORAL SQUAMOUS CELL CARCINOMA: A REVIEW
Aim & background: In spite of increase in the incidence of oral squamous cell carcinoma, there are not serious achievements gained in related treatment modalities and survival rates. Hence, through identifying the etiolo...
BIOPSY RESULTS OF CERVICAL LYMPHADENOPATHY AT TERTIARY CARE UNIT
Background: Cervical lymphadenopathy is a very common complication of many diseases e.g. bacterial and viral infection, tuberculosis, lymphomas, malignancy and autoimmune diseases. In Pakistan, according to many studies...
MEDICINAL USES OF GUDUCHI SATVA (TINOSPORA CORDIFOLIA): A REVIEW ARTICLE
Guduchi Satva (GS), the starchy material extracted from the Guduchi stem is well-known Ayurvedic single drug formulation having a wide range of therapeutic utility. Species of the plant, stem size, collection time, seaso...
MOLECULAR CHARACTERISATION OF HOOKWORM DETECTED FROM PEASANT FARMERS IN SELECTED LOCAL GOVERNMENT AREAS OF KADUNA STATE, NIGERIA
This study aimed at detecting the human hookworm species among peasant farmers in selected Local Government Areas (LGAs) of Kaduna State, Nigeria. A cross sectional, descriptive study was carried out between November 201...