Association of mean platelet volume and platelet distribution width with diabetic retinopathy in patients with diabetes mellitus

Journal Title: Indian Journal of Clinical and Experimental Ophthalmology - Year 2018, Vol 4, Issue 4

Abstract

Introduction MPV and PDW are indicators of subclinical platelet hyperactivity and can be used as predictive factors for development and progression of diabetic retinopathyMaterials and Methods This prospective case control study enrolled 150 patients with diabetic retinopathy DR group and 150 diabetic patients without retinopathy control group Detailed history and ophthalmic examination was done The DR group was divided into 5 subgroups according to the ETDRS classification of diabetic retinopathy MPV PDW FBS and PPBS values were obtainedResult The mean value of MPV in DR group was higher compared to control group p0016 PDW also followed the similar trend with DR group having mean value of 1371 136 fl and control group having 1213 129 fl p0023 The study also found a trend of increase in severity of diabetic retinopathy with increasing level of MPV and PDW However a statistically significant association was found only between MPV and stage of diabetic retinopathy r 0214 p 0046 A marked increase in MPV and PDW values were found in those with Proliferative diabetic retinopathy pConclusion Platelet indices like MPV can be a cheap and easy to measure tool for monitoring diabetic retinopathyKeywords Mean platelet volume Platelet distribution width Diabetic retinopathy Proliferative diabetic retinopathy

Authors and Affiliations

Shubhratha S. Hegde, Mahima S. R, Sandhya Dharwadkar, Mohammad Abdul Kayoom N, Shashidhar H. B

Keywords

Related Articles

A comparative study on pterygium excision and glue free limbal conjunctival autograft with and without suture

Aim: A comparative study on pterygium excision and glue free limbal conjunctival autograft with and without suture. Materials and Methods: 50 patients of primary nasal pterygium attending ophthalmology OPD in Rotary Hosp...

Refraction-seeking behaviour among young people presenting to a medical college hospital of Bihar

With an objective to enquire about availability of primary or secondary level facilities for refraction and explore reasons for approaching a tertiary OPD despite awareness of the same a prospective study was conducted o...

Correlation of visual acuity and contrast sensitivity in visually disabled patients of moderate to severe diabetic retinopathy

Purpose Aims of this study is to characterise the visual disability of patients of moderate to severe diabetic retinopathy in terms of logarithm of minimum angle of resolution LogMAR visual acuity and contrast sensitivit...

Comparison of macular thickness in myopia, hypermetropia and emmetropia: An OCT based study

Aim To make a comparative evaluation of macular thickness in myopia and hypermetropia versus emmetropiaMaterials and Methods A crosssectional OCT based study was done in randomly selected 100 emmetropes 93 myopes 67 hype...

Download PDF file
  • EP ID EP474870
  • DOI 10.18231/2395-1451.2018.0119
  • Views 83
  • Downloads 0

How To Cite

Shubhratha S. Hegde, Mahima S. R, Sandhya Dharwadkar, Mohammad Abdul Kayoom N, Shashidhar H. B (2018). Association of mean platelet volume and platelet distribution width with diabetic retinopathy in patients with diabetes mellitus. Indian Journal of Clinical and Experimental Ophthalmology, 4(4), 530-534. https://europub.co.uk/articles/-A-474870