Association of Mean Platelet Volume and Platelet Distribution Width with Hba1c
Journal Title: Journal of Endocrinology and Diabetes - Year 2017, Vol 4, Issue 4
Abstract
Diabetes mellitus type 2 (DMT2) is a metabolic disorder, and its prevalence is rising worldwide. The objective of the study was to investigate association of mean platelet volume (MPV) and platelet distribution width (PDW) with glycemic control marker HbA1c. So that MPV, PDW could be used as a prognosticators of deterioration of glucoregulation in diabetes mellitus type 2 instead of HbA1c value. This study included 87 DMT2 patients, which divided into two groups, A (n=41, presence in diabetics ≤ 6.5 – 6.9%) and B (n=46, target in diabetes ≥ 7.0%), according to HbA1c values. Spearsman correlation co-efficients were calculated to evaluate the relationship between MPV, PDW and HbA1c value. Binominal logistic regression analysis was performed to estimate the relationship between glycemic control, as dichotomous outcome of MPV and PDW as the main prognosticator. MPV and PDW were significantly higher in the group B compared to the group A. Significant positive correlations of MPV with Random Blood Sugar (RBS) and HbA1c value were found in the total sample. MPV and PDW correlate with glycemic control markers in DMT2 patients. In conclusion, MPV and PDW could be used as simple and cost effective prognosticators of deterioration of glucoregulation.
Authors and Affiliations
Sadikuj Jaman, Sawgat Rezwan, Sakibul Alam, Rayhanul Islam, Asma Ul Husna, Abu Sayeed
Keywords
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- EP ID EP333818
- DOI 10.15226/2374-6890/4/4/00183
- Views 98
- Downloads 0
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