Association of Pattern of Bacteria Sensitivity During the Empirical Antibiotics Use to the Achievement of Clinical Outcome in Pediatric Patients with Pneumonia
Journal Title: Indonesian Journal of Clinical Pharmacy - Year 2014, Vol 3, Issue 4
Abstract
Pneumonia is one of infectious diseases that require a comprehensive and effective effort in its treatment, including in the use of empirical antibiotics. The use of empirical antibiotics should be based on patterns of sensitivity toward bacteria. The aim of this study was to evaluate the use of antibiotics based on the sensitivity patterns by clinical outcomes as the goal of treatment. This study was conducted in Hasan Sadikin Hospital Bandung in October–December 2013 using a retrospective cross-sectional study design. Secondary data were obtained from medical records during January 2011–December 2012. This study consisted of 24 patients with positive culture test and received antibiotic prescription. The results showed the percentage of the use of cefotaxime-ampicillin (37.5%), cefotaxime (33.3%), ceftriaxone (20.8%), and ampicillin (8.4%). The most influential antibiotics for achieving clinical outcome using 95% confidence level is combination of cefotaxime-ampiciline (p=0.044) with 77.7% sensitivity level. This study suggested that the pattern of antibiotic sensitivity affected the clinical outcomes of pediatric patients with pneumonia.
Authors and Affiliations
Vesara A. Gatera, Ahmad Muhtadi, Eli Halimah, Dwi Prasetyo
Keywords
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- EP ID EP336911
- DOI 10.15416/ijcp.2014.3.4.127
- Views 81
- Downloads 0
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